Background: Exercise is widely known to lower intraocular pressure and increase ocular blood flow, which may be beneficial for glaucoma management. However, there are few studies that have reported on the relationship between exercise and glaucoma progression. The aim of our study was to investigate the exercise habits of those with primary open angle glaucoma (POAG) and its association with the progression of visual field (VF) loss.

Methods: Daily physical activity (PA) was monitored by an accelerometer (ActiGraph wGT3x-BT) which patients wore for more than 10 h of being awake on their right wrists for 1 week.

Results: Seventy-one non-progressive and 27 progressive patients were enrolled in the study. 24-h moderate to vigorous physical activity (MVPA) exercise showed that POAG patients had similar variation trends consisting of 3 wave peaks and 2 wave hollows. Minutes spent in MVPA was 19.89 ± 15.81 and 21.62 ± 15.10 during 07:00-09:00 h ( = 0.204), 15.40 ± 14.49 and 15.67 ± 12.43 during 15:00-17:00 h ( = 0.822) and 17.26 ± 21.11 and 11.42 ± 11.58 during 18:00-20:00 h ( = 0.001) in the non-progressive and progressive group, respectively. Univariate analysis indicated that 10 min of MVPA (18:00-20:00 h) [odds ratio, OR (95% CI) = 0.82 (0.73, 0.92)], average mean arterial pressure [OR (95% CI) = 0.96 (0.94, 0.98)], age [OR (95% CI) = 1.06 (1.03, 1.08)], male [OR (95% CI) = 0.67 (0.48, 0.96)], spherical equivalent [OR (95% CI) = 1.14 (1.07, 1.22)] and IOP-lowering medications [OR (95% CI) = 1.54 (1.16, 2.05)] were significantly correlated with having progressive VF damage. Multivariable analysis showed that 10 min of MVPA (18:00-20:00 h) [OR (95% CI) = 0.85 (0.75, 0.97)] was associated with progressive VF loss even after adjusting for other risk factors.

Conclusions: Evening exercise may lower the odds of VF progression, suggesting that exercise habits possibly play an important role in glaucoma progression.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049389PMC
http://dx.doi.org/10.1186/s40662-020-0175-9DOI Listing

Publication Analysis

Top Keywords

[or 95%
24
evening exercise
8
lower odds
8
visual field
8
primary open
8
open angle
8
angle glaucoma
8
exercise lower
8
glaucoma progression
8
exercise habits
8

Similar Publications

Article Synopsis
  • The study measured fibrinogen fluorescence at temperatures between 20 and 80 degrees Celsius across different pH levels.
  • It was found that raising the temperature from 20 to 40 degrees Celsius did not change the structure of fibrinogen in solutions with pH between 4.5 and 9.3.
  • However, temperatures between 40 to 50 degrees Celsius caused some structural changes in neutral solutions, and temperatures above 50-55 degrees Celsius led to significant denaturation of the fibrinogen molecule.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!