Severe Immune Thrombocytopenia in a Patient with HIV-HCV Co-infection: Challenges in Management.

Immune thrombocytopenia is a well-known complication of both HIV and Hepatitis C virus infections. Management becomes challenging when a patient with HCV-HIV co-infection presents with severe thrombocytopenia. Adverse drug reactions and drug interactions has to be considered while choosing treatment options for such patients. We report such a case which illustrates the difficulty in managing severe thrombocytopenia in HCV-HIV co-infected patients where evidence based clinical decision making helped in choosing the right therapy for the patient.