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The international trial of nasal oxygen therapy after cardiac surgery (NOTACS) in patients at high risk of postoperative pulmonary complications: Economic evaluation protocol and analysis plan.
PLoS One
January 2025
School of Life Course and Population Sciences, King's College London, London, United Kingdom.
Introduction: High-Flow Nasal Therapy (HFNT) is an innovative non-invasive form of respiratory support. Compared to standard oxygen therapy (SOT), there is an equipoise regarding the effect of HFNT on patient-centred outcomes among those at high risk of developing postoperative pulmonary complications after undergoing cardiac surgery. The NOTACS trial aims to determine the clinical and cost-effectiveness of HFNT compared to SOT within 90 days of surgery in the United Kingdom, Australia, and New Zealand.
View Article and Find Full Text PDFEnhanced Gain Extrapolation Technique: A Third-Order Scattering Approach For High-Accuracy Antenna Gain, Sparse Sampling, At Fresnel Distances.
IEEE Trans Antennas Propag
December 2024
National Institute of Standards and Technology, Boulder CO 80305.
In this paper we describe an enhanced three-antenna gain extrapolation technique that allows one to determine antenna gain with significantly fewer data points and at closer distances than with the well-established traditional three-antenna gain extrapolation technique that has been in use for over five decades. As opposed to the traditional gain extrapolation technique, where high-order scattering is purposely ignored so as to isolate only the direct antenna-to-antenna coupling, we show that by incorporating third-order scattering the enhanced gain extrapolation technique can be obtained. The theoretical foundation using third-order scattering is developed and experimental results are presented comparing the enhanced technique and traditional technique for two sets of internationally recognized NIST reference standard gain horn antennas at X-band and Ku-band.
View Article and Find Full Text PDFBackground: Childhood cancer is not a high priority in health care financing for many countries, including in Ghana. Delayed care seeking and treatment abandonment, often due to the financial burden of care seeking to families, are common reasons for a relatively low overall survival (OS) in low-and middle-income countries. In this study, we analyzed the cost-effectiveness of extending health insurance coverage to children with Burkitt lymphoma (BL) in Ghana.
View Article and Find Full Text PDFThe interplay of uncertainty, relevance and learning influences auditory categorization.
Sci Rep
January 2025
Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA, USA.
Auditory perception requires categorizing sound sequences, such as speech or music, into classes, such as syllables or notes. Auditory categorization depends not only on the acoustic waveform, but also on variability and uncertainty in how the listener perceives the sound - including sensory and stimulus uncertainty, the listener's estimated relevance of the particular sound to the task, and their ability to learn the past statistics of the acoustic environment. Whereas these factors have been studied in isolation, whether and how these factors interact to shape categorization remains unknown.
View Article and Find Full Text PDFUrban pandemic governance personal protective equipment allocation strategies: a system dynamics simulation.
Sci Rep
January 2025
Institute for Disaster Management and Reconstruction, Sichuan University, No. 122, Section 1, Huanghe Middle Road, Chengdu, 610211, China.
In the early days of the urban pandemic, many cities had personal protective equipment (PPE) shortages, which adversely affected urban pandemic governance. Using the COVID-19 strategies employed in Wuhan as the pivotal case study, this study sought to determine effective strategies to optimize city PPE distribution. System dynamics modeling was employed to explore the influence of PPE allocation strategies on pandemic control measures.
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