A new risk/treatment needs protocol for assessing "juveniles with sex offenses" operationalized in the Treatment Needs and Progress Scale (TNPS) was recently introduced, prompting quick embrace before any serious examination. This article critiques the proposed protocol and TNPS. Highlighted are misleading statements, substantial omissions related to review of research, and significant margins of TNPS underpinnings that cause considerable pause. Target population, essential to adopting and implementing TNPS, is not clearly stated. Multiple basic rudimentary steps are missing in the research protocol for two age groups. The "new" protocol appears to be a re-installment of the old one, applying templates from adult tools and empirical findings on adults to adolescents, thus treating youth like adults, an outdated stance in contemporary research and clinical practice related to risk assessment of sexually abusive youth..
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http://dx.doi.org/10.1080/10538712.2020.1733161 | DOI Listing |
JMIR Form Res
January 2025
Department of Medical Informatics, Amsterdam UMC - University of Amsterdam, Amsterdam, Netherlands.
Background: The prognosis for patients with several types of cancer has substantially improved following the introduction of immune checkpoint inhibitors, a novel type of immunotherapy. However, patients may experience symptoms both from the cancer itself and from the medication. A prototype of the eHealth tool Cancer Patients Better Life Experience (CAPABLE) was developed to facilitate symptom management, aimed at patients with melanoma and renal cell carcinoma treated with immunotherapy.
View Article and Find Full Text PDFAnnu Rev Anal Chem (Palo Alto Calif)
January 2025
Department of Chemistry, Michigan State University, East Lansing, Michigan, USA; email:
Mass spectrometry (MS)-based top-down proteomics (TDP) characterizes proteoforms in cells, tissues, and biological fluids (e.g., human plasma) to better our understanding of protein function and to discover new protein biomarkers for disease diagnosis and therapeutic development.
View Article and Find Full Text PDFPLoS One
January 2025
College of Veterinary Medicine and Animal Science, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
This work aimed to evaluate the use of Visible and Near-infrared Spectroscopy (Vis-NIRS) as a tool in the classification of bovine carcasses. A total of 133 animals (77 females, 29 males surgically castrated and 27 males immunologically castrated) were used. Vis-NIRS spectra were collected in a chilling room 24 h postmortem directly on the hanging carcasses over the longissimus thoracis between the surface of the 5th and 6th ribs.
View Article and Find Full Text PDFPLoS One
January 2025
Jinan University, Guangzhou, China.
Objective: This study aimed to develop and validate a nomogram to predict the risk of sepsis in non-traumatic subarachnoid hemorrhage (SAH) patients using data from the MIMIC-IV database.
Methods: A total of 803 SAH patients meeting the inclusion criteria were randomly divided into a training set (563 cases) and a validation set (240 cases). Independent prognostic factors were identified through forward stepwise logistic regression, and a nomogram was created based on these factors.
Environ Toxicol Chem
January 2025
Windward Environmental LLC, Seattle, WA, USA.
Monitoring selenium (Se) concentrations in fish ovaries is an important tool for evaluating the ecological risk posed by Se in aquatic systems. Most guidance recommends sampling fish ovaries as closely as possible to when fish spawn on the premise that Se is mobilized from the liver to the ovary during vitellogenesis, and therefore, sampling ovaries during the early phases of oocyte maturation may underestimate egg Se concentrations at the time of spawning. In this study, we evaluated ovary Se data from two species with synchronous oocyte development (Ptychocheilus oregonensis and Prosopium williamsoni), one species with asynchronous oocyte development (Richardsonius balteatus), and one where the mode of development is unclear (Mylocheilus caurinus).
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