Post-extubation stridor after prolonged intubation in the pediatric intensive care unit (PICU): a prospective observational cohort study.

Eur Arch Otorhinolaryngol

Department of Otorhinolaryngology and Head and Neck Surgery, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.

Published: June 2020

AI Article Synopsis

  • The study investigated the incidence of post-extubation stridor in children who underwent prolonged endotracheal intubation, identifying it as a significant symptom of laryngeal damage.
  • Out of 150 children studied, 18.7% experienced stridor after being extubated, with a small number requiring reintubation or surgical intervention.
  • Key factors linked to increased risk of stridor included intubation happening on-site, usage of cuffed tubes, and younger age, highlighting the importance of recognizing these factors to reduce laryngeal injury.

Article Abstract

Purpose: Prolonged endotracheal intubation may lead to laryngeal damage, with stridor being the most relevant clinical symptom. Our objective was to determine the incidence of post-extubation stridor and their clinical consequences in children within a tertiary referral center and to identify contributing factors.

Methods: 150 children, aged 0-16 years, intubated for more than 24 h were prospectively enrolled until discharge of the hospital. Potential relevant factors, thought to mediate the risk of laryngeal damage, were recorded and analyzed.

Results: The median duration of intubation was 4 days, ranging from 1 to 31 days. Stridor following extubation occurred in 28 patients (18.7%); 3 of them required reintubation due to respiratory distress and in 1 child stridor persisted for which a surgical intervention was necessary. In multivariate analyses, we found the following independent predictors of stridor: intubation on the scene, the use of cuffed tubes and lower age.

Conclusion: Despite a high incidence for post-extubation stridor, only few children need reintubation or surgical intervention as a result of post-extubation lesions. Intubation on the scene, the use of cuffed tubes and young age are associated with a significant increased risk of post-extubation stridor. Awareness of these factors gives the possibility to anticipate on the situation and to minimize laryngeal injury and its possible future consequences.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198633PMC
http://dx.doi.org/10.1007/s00405-020-05877-0DOI Listing

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