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Inherited genome instability.
Science
January 2025
Spanish National Cancer Research Center (CNIO), Madrid, Spain.
Germline structural variants are a risk factor for pediatric extracranial solid tumors.
View Article and Find Full Text PDFOnline Portal Use of Pathology Reports in Patients With Solid Tumors.
Arch Pathol Lab Med
December 2024
the Department of Pathology, Medical College of Wisconsin, Milwaukee (Jorns).
Context.—: Patients can now immediately review pathology reports via online health portals.
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Molecular insights unlocking therapeutic potential for multiple myeloma and bone disease management.
J Exp Clin Cancer Res
December 2024
Department of Health Sciences, Magna Graecia University of Catanzaro, 88100, Catanzaro, Italy.
Multiple myeloma (MM), a hematologic malignancy characterized by the clonal expansion of plasma cells within the bone marrow, is associated with severe health complications, including osteolytic bone lesions that significantly increase the risk of fractures, leading to higher morbidity and mortality rates. One intriguing protein in this context is the RNA polymerase binding factor Che-1/AATF (Che-1), which has emerged as a potential player in the survival and proliferation of myeloma cells. Hippo pathway has been shown to be an important mediator of oncogenesis in solid tumors, especially for its role in shaping a tumor microenvironment favorable to cancer maintenance and spread.
View Article and Find Full Text PDFReconsideration of the clinical management of hepatic hemangioma.
World J Gastrointest Surg
November 2024
Division of Liver Surgery, Department of General Surgery and Laboratory of Liver Surgery, and State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Article Synopsis
- * The proposed grading system aims to enhance clinical management, especially for patients who experience symptoms or complications.
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Photothermal spectroscopy on-chip sensor for the measurement of a PMMA film using a silicon nitride micro-ring resonator and an external cavity quantum cascade laser.
Nanophotonics
May 2024
Centre for Advanced Photonics and Process Analysis, Munster Technological University, T12 T66T Bishopstown, Cork, Ireland.
Article Synopsis
- - Laser-based mid-IR photothermal spectroscopy (PTS) is a rapid and sensitive analytical method that utilizes advanced laser technology to capture the absorption characteristics of various materials, such as liquids or solids.
- - This study utilizes an external cavity quantum cascade laser (EC-QCL) to analyze a thin film of polymethyl methacrylate (PMMA) on a silicon nitride micro-ring resonator, demonstrating its effectiveness in creating an on-chip photothermal sensor.
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