Sampling lesbian, gay, and bisexual (LGB) people to recruit a national probability sample is challenging for many reasons, including the low base rate of LGB people in the population. To address this challenge, researchers have relied on diverse approaches to sampling LGB people. We aimed to test an innovative method to assemble a U.S. national probability sample of non-transgender sexual minority adults. Our approach used two phases. In Phase 1, we identified LGBT respondents in a probability general population sample. These respondents were then queried about their sexual orientation and gender identity using short screening questions to identify non-transgender sexual minority respondents. In Phase 2, the identified sexual minority respondents completed the targeted survey online or on a mailed questionnaire. In Phase 1, using random-digit dialing, a nationally representative sample of 366,644 respondents were screened in a brief telephone interview. Of them, 3.5% ( = 12,837) identified as LGB or transgender. In Phase 2, eligible respondents were asked to participate in a self-administered survey questionnaire. Eligibility was based on gender identity, age, race and ethnicity, and educational restrictions. Of the 3525 who were eligible, 81% ( = 2840) agreed to participate in the study (78% agreed to use the web version and 22% the mailed questionnaire), and 49% of web surveys and 46% of mailed surveys were completed. The final sample included 1331 respondents. The benefits of this approach include the ability to assess sexual minority-specific content in a national probability sample; challenges include high cost and low base rates for Asian and American Indian or Alaska Native individuals in the United States.
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http://dx.doi.org/10.1089/lgbt.2019.0145 | DOI Listing |
Anal Bioanal Chem
January 2025
Statistical Engineering Division, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD, 20899-8980, USA.
Closely related species of Salmonidae, including Pacific and Atlantic salmon, can be distinguished from one another based on nucleotide sequences from the cytochrome c oxidase sub-unit 1 mitochondrial gene (COI), using ensembles of fragments aligned to genetic barcodes that serve as digital proxies for the relevant species. This is accomplished by exploiting both the nucleotide sequences and their quality scores recorded in a FASTQ file obtained via Next Generation (NextGen) Sequencing of mitochondrial DNA extracted from Coho salmon caught with hook and line in the Gulf of Alaska. The alignment is done using MUSCLE (Muscle 5.
View Article and Find Full Text PDFJ Bone Miner Metab
January 2025
Deakin University, IMPACT- Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Geelong, Australia.
Introduction: Impact microindentation (IMI) measures bone material strength index (BMSi) in vivo. However, its ability to predict fractures is still uncertain. This study aimed to determine the association between BMSi and 10 year fracture probability, as calculated by the FRAX algorithm.
View Article and Find Full Text PDFFASEB J
January 2025
Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 200011, China.
With the global rise in advanced maternal age (AMA) pregnancies, the risk of gestational diabetes mellitus (GDM) increases. However, few GDM prediction models are tailored for AMA women. This study aims to develop a practical risk prediction model for GDM in AMA women.
View Article and Find Full Text PDFCPT Pharmacometrics Syst Pharmacol
January 2025
Department of Pharmacy, Uppsala University, Uppsala, Sweden.
Type 2 diabetes (T2D) is a progressive metabolic disorder that could be an underlying cause of long-term complications that increase mortality. The assessment of the probability of such events could be essential for mortality risk management. This work aimed to establish a framework for risk predictions of macrovascular complications (MVC) and diabetic kidney disease (DKD) in patients with T2D, using real-world data from the Swedish National Diabetes Registry (NDR), in the presence of mortality as a competing risk.
View Article and Find Full Text PDFNutr J
January 2025
Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Objective: This study aims to evaluate the relationship between apolipoproteins (ApoA1, ApoB, and the ApoB/A1 ratio) and the incidence of major adverse cardiovascular events (MACE) in patients with coronary artery disease (CAD) and impaired kidney function, assessing their potential role in secondary prevention.
Method: A prospective cohort of 1,640 patients with impaired kidney function who underwent percutaneous coronary intervention in China was analyzed. Patients were categorized based on the measurements of ApoA1, ApoB, and ApoB/A1 ratio.
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