Methylene tetrahydrofolate reductase (MTHFR) gene mutations could be the cause of infertility in hypothyroid patients. Hence, it is worthy to screen for MTHFR gene mutations in infertile hypothyroid females and their partners if infertility persists after optimizing thyroid function.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044389PMC
http://dx.doi.org/10.1002/ccr3.2654DOI Listing

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