[This retracts the article DOI: 10.1021/acscentsci.9b00224.].

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047427PMC
http://dx.doi.org/10.1021/acscentsci.0c00021DOI Listing

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Article Synopsis
  • Migrasomes are new organelles important for cell signaling and communication that involve the protein TSPAN4, whose role in cancer is not well understood.
  • Researchers studied TSPAN4 across multiple cancer types, examining its expression levels and connections to tumor characteristics using large datasets.
  • Findings indicate TSPAN4 is irregularly expressed in tumors, affecting tumor growth and immune response, particularly in glioma, where it encourages an immunosuppressive environment.
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Background: Endoscopic endonasal techniques, initially developed for sinonasal tumor resection, have revolutionized the approach to orbital lesions. The emergence of endonasal orbital tumor surgery has prompted anatomical studies focusing on the medial orbit, yet there remains a lack of literature on maneuverability lateral to the optic nerve (ON), with current feasibility assessments relying primarily on the plane of resectability (POR).

Methods: Bilateral anatomical dissections were conducted on four latex-injected human cadaveric heads using an endoscopic medial and inferior orbitotomy and superomedial displacement of the inferior rectus muscle (IRM) to access the inferolateral intraconal quadrant.

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