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Importation of Extensively Drug-Resistant Salmonella enterica Serovar Typhi Cases in Ontario, Canada. | LitMetric
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Importation of Extensively Drug-Resistant Salmonella enterica Serovar Typhi Cases in Ontario, Canada.

Alireza Eshaghi Sandra Zittermann Amrita Bharat Michael R Mulvey Vanessa G Allen Samir N Patel

Antimicrob Agents Chemother

Public Health Ontario Laboratory, Public Health Ontario, Toronto, Ontario, Canada

Published: April 2020

A strain of extensively drug-resistant (XDR) serovar Typhi has caused a large ongoing outbreak in Pakistan since 2016. In Ontario, Canada, 10 cases of mainly bloodstream infections ( = 9) were identified in patients who traveled to Pakistan. Whole-genome sequencing showed that Canadian cases were genetically related to the Pakistan outbreak strain. The appearance of XDR typhoid cases in Ontario prompted a provincial wide alert to physicians to recommend treatment with carbapenems or azithromycin in suspected typhoid cases with travel history to Pakistan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179602PMC
http://dx.doi.org/10.1128/AAC.02581-19DOI Listing

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