Herein, a novel synthesis method of colloidal GdPO:Mn,Eu nanoparticles for luminescent nanothermometry is proposed. XRD, TEM, DLS, and zeta potential measurements confirmed the crystallographic purity and reproducible morphology of the obtained nanoparticles. The spectroscopic properties of GdPO:Mn,Eu with different amounts of Mn and Eu were analyzed in a physiological temperature range. It was found that GdPO:1%Eu,10%Mn nanoparticles revealed extraordinary performance for noncontact temperature sensing with relative sensitivity S = 8.88%/°C at 32 °C. Furthermore, the biocompatibility and safety of GdPO:15%Mn,1%Eu was confirmed by cytotoxicity studies. These results indicated that colloidal GdPO doped with Mn and Eu is a very promising candidate as a luminescent nanothermometer for in vitro applications.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152838PMC
http://dx.doi.org/10.3390/nano10030421DOI Listing

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