Germline stem cell aging in the Drosophila ovary.

Curr Opin Insect Sci

Department of Biochemistry, Institute for Stem Cell and Regenerative Medicine, University of Washington, 850 Republican St, Seattle, WA 98109, United States. Electronic address:

Published: February 2020

The age-related decline of adult stem cells leads to loss of tissue homeostasis and contributes to organismal aging. Though the phenotypic hallmarks of aging are well-characterized at the organ or tissue level, the molecular processes that govern stem cell aging remain unclear. This review seeks to highlight recent research in stem cell aging in the Drosophila ovary and connect the discoveries in the fly to ongoing questions in stem cell aging.

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Source
http://dx.doi.org/10.1016/j.cois.2019.11.003DOI Listing

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