A source of treatment refractoriness in immune cytopenias appears to be residual CD138/38-positive lymphocyte populations. A short course of daratumumab is a novel treatment of refractory thrombocytopenia after failure of standard treatment options.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065484PMC
http://dx.doi.org/10.1182/bloodadvances.2019001215DOI Listing

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