The scale-up of chemoenzymatic bromolactonization to 100 g scale is presented, together with an identification of current limitations. The preparative-scale reaction also allowed for meaningful mass balances identifying current bottlenecks of the chemoenzymatic reaction.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045808 | PMC |
| http://dx.doi.org/10.1021/acssuschemeng.9b07494 | DOI Listing |
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