AI Article Synopsis
- A genome-wide association study on Italian buffalo identified three significant single nucleotide polymorphisms (SNPs) linked to different aspects of mammary gland morphology, including anterior and posterior teat lengths.
- Two genomic regions on chromosomes 10 and 20 showed significant signals for mammary gland characteristics, with chromosome 10 housing potential candidate genes ACTC1 and GJD2 that may influence mammary development.
- The findings contribute valuable information on the genetic factors affecting buffalo mammary gland morphology, enhancing understanding of mammary growth regulation.
Article Abstract
This research communication describes a genome-wide association study for Italian buffalo mammary gland morphology. Three single nucleotide polymorphisms (AX-85117983, AX-8509475 and AX-85117518) were identified to be significantly associated with buffalo anterior teat length, posterior teat length and distance between anterior and posterior teat, respectively. Two significant signals for buffalo mammary gland morphology were observed in two genomic regions on the chromosome 10, and chromosome 20. One of the regions located on the chromosome 10 has the most likely candidate genes ACTC1 and GJD2, both of which have putative roles in the regulation of mammary gland development. This study provides new insights into the genetic variants of buffalo mammary gland morphology and may be beneficial for understanding of the genetic regulation of mammary growth.
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| http://dx.doi.org/10.1017/S0022029919000967 | DOI Listing |
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