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Alternative splicing of vascular calcification: Insights, opportunities, and challenges.
Cell Signal
January 2025
Jinhua Advanced Research Institute, Jinhua 321019, China. Electronic address:
Vascular calcification(VC) significantly increases the risk of cardiovascular events, leading to thickening of the myocardium and arteries, coronary heart disease, heart failure, and potentially triggering myocardial infarction and sudden cardiac death. Although VC is a reversible process, there are currently no methods or medications in clinical practice that can completely reverse or cure it. The current treatment strategies primarily focus on slowing the progression of VC and exploring new diagnostic and therapeutic approaches, making the identification of early diagnostic markers for VC particularly important.
View Article and Find Full Text PDFUnderstanding the Support Needs of People with Autosomal Dominant Polycystic Kidney Disease: A Qualitative Phenomenological Descriptive Study.
Nephron
January 2025
Department of Renal Medicine, Aarhus University Hospital, Aarhus, Denmark.
Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is a prevalent hereditary kidney disease and the fourth most common cause of kidney failure. Patients may be aware of their condition from an early age or discover it unexpectedly, with varying levels of familial knowledge about the disease. This chronic condition presents significant challenges for healthcare professionals.
View Article and Find Full Text PDFMixed discipline 'Simulation Integrating Metal and Physical health Learning' (SMIPL): A qualitative study of student experience and learning.
Nurse Educ Today
January 2025
Lecturer in Nursing Education, Faculty of Nursing, Midwifery & Palliative Care, King's College London, 57 Waterloo Road, London, SE1 8WA. Electronic address:
Background/problems: Individuals with comorbid physical and mental health conditions face significant threats to their well-being while placing a substantial burden on healthcare systems through increased service costs. Nursing professionals encounter multiple challenges in delivering effective care to this population. These challenges include a lack of integrated care models, communication barriers among providers, the complexity of addressing dual health needs, insufficient training in comorbidity management, resource and time constraints, and pervasive stigma toward mental illness.
View Article and Find Full Text PDFPreoperative Anxiety Management Practices in Pediatric Anesthesia: Comparative Analysis of an Online Survey Presented to Experts and Social Media Users.
JMIR Pediatr Parent
January 2025
Department of Anesthesiology, University Medical Center Goettingen, Goettingen, Germany.
Background: Managing preoperative anxiety in pediatric anesthesia is challenging, as it impacts patient cooperation and postoperative outcomes. Both pharmacological and nonpharmacological interventions are used to reduce children's anxiety levels. However, the optimal approach remains debated, with evidence-based guidelines still lacking.
View Article and Find Full Text PDFA Qualitative Study on Nurses' Caring Experiences With Individuals With Kidney Failure Receiving Haemodialysis.
J Ren Care
March 2025
Department of Emergency and Critical Care Nursing, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Background: Kidney failure is a major health issue globally, particularly in Ghana and other low- and middle-income countries. Nurses are centrally involved in the direct care and technical operations of managing individuals with kidney failure, and they have first-hand exposure to the complexities of kidney failure management, including haemodialysis within resource-constrained settings.
Objective: This study explored the experiences of nurses who provide care to individuals with kidney failure receiving haemodialysis in Ghana.
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