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Intense 68Ga-Pentixafor Activity in Aldosterone-Producing Adrenal Adenomas. | LitMetric

Intense 68Ga-Pentixafor Activity in Aldosterone-Producing Adrenal Adenomas.

Clin Nucl Med

From the Department of Nuclear Medicine and Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine.

Published: April 2020

AI Article Synopsis

  • Ga-pentixafor is a ligand for CXCR4 and shows promise as a PET tracer for assessing different medical conditions.
  • The text discusses its notable effectiveness in PET/CT imaging for two patients diagnosed with adrenal adenomas.
  • These adenomas were identified as the underlying cause of the patients' Conn syndrome, a condition related to hormonal imbalance.

Article Abstract

Ga-pentixafor, a ligand of CXCR4 (CXC chemokine receptor type 4), has been reported as a potential PET tracer to evaluate a variety of pathological entities. We report intense Ga-pentixafor activity on PET/CT in 2 patients in the histopathologically confirmed adrenal adenomas, which were the cause of their Conn syndrome.

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Source
http://dx.doi.org/10.1097/RLU.0000000000002946DOI Listing

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