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Long-term debridement effect of denervated large sacrococcygeal pressure injury: A case report.
Medicine (Baltimore)
January 2024
Department of Orthopedics, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin Province, China.
Rationale: Complicated pressure injury in paraplegic patients is common and difficult to manage. Previous case studies have documented short-term management; however, little is known regarding suitable approaches to long-term clearing of extensive pressure injury in the sacrococcygeal area under denervation.
Patient Concerns: A 53-year-old man was bedridden for 1.
Influence of Chitin Source and Polymorphism on Powder Compression and Compaction: Application in Drug Delivery.
Molecules
November 2020
Research and Innovation Centre, The Jordanian Pharmaceutical Manufacturing Company (JPM), P.O. Box 94, Naor 11710, Jordan.
The objective of the research reported herein is to compare the compaction properties of three different chitin extracts from the organisms most used in the seafood industry; namely crabs, shrimps and squids. The foregoing is examined in relation to their polymorphic forms as well as compression and compaction behavior. Chitin extracted from crabs and shrimps exhibits the α-polymorphic form whilst chitin extracted from squid pins displays a β-polymorphic form.
View Article and Find Full Text PDFStudy of the Tableting Properties of MCR, a Newly Coprocessed Cellulose-based Direct Compression Excipient.
Turk J Pharm Sci
June 2019
Al Jouf University, Pharmacy College, Department of Pharmaceutics, Sekake, Saudi Arabia.
Objectives: In this work, the aim was to coprocess and evaluate a new cellulose-based direct compression tableting excipient (MCR) of improved functionalities by granulation and slugging from locally extracted microcrystalline cellulose and regenerated cellulose (CRC).
Materials And Methods: Model tablet formulations of metronidazole (MZ) as a model of nonfreely flowing and directly incompressible active pharmaceutical ingredient were designed to study the tableting properties of MCR.
Results: The results showed that the optimum concentration of CRC needed to produce excipient of accepted flow properties and high compression characteristics was 20% w/w.
Crushed Metronidazole in Managing Chronic Nonsurgical Wound Malodor in Patients with Cancer: Preliminary Findings.
J Palliat Med
March 2020
Department of Palliative Care, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Understanding the Performance of a Novel Direct Compression Excipient Comprising Roller Compacted Chitin.
Mar Drugs
February 2020
Research and Innovation Centre, The Jordanian Pharmaceutical Manufacturing Company (JPM), P.O. Box 94, Naor 11710, Jordan.
Chitin has been investigated in the context of finding new excipients suitable for direct compression, when subjected to roller compaction. Ball milling was concurrently carried out to compare effects from different energy or stress-inducing techniques. Samples of chitin powders (raw, processed, dried and humidified) were compared for variations in morphology, X-ray diffraction patterns, densities, FT-IR, flowability, compressibility and compactibility.
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