Sarcoidosis is a systemic granulomatous disease of unknown cause. Skin involvement may be specific lesions in which granulomas are detected on biopsy or nonspecific lesions without granulomatous inflammation on biopsy. Lupus pernio (LP) occurs in the form of smooth, bright nodules and plaques on the nose, ear, lips, and cheeks. Although presence of skin involvement is frequent, lupus perio is reported as a rare form of extrapulmonary sarcoidosis. A 57-year-old female patient applied to the dermatology outpatient clinic with a lesion on the nose. We report a case of chronic sarcoidosis presenting with lupus pernio with clinical and radiological improvement.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/00325481.2020.1733863 | DOI Listing |
Clin Exp Dermatol
January 2025
Department of Dermatology, Our Lady of Lourdes Hospital, Drogheda, Louth, Ireland.
Clin Dermatol
December 2024
Department of Dermatology, Yale School of Medicine, 333 Cedar St, LMP 5040, PO Box 208059, New Haven, Connecticut, 06510, United States. Electronic address:
Sarcoidosis is a multisystem inflammatory disorder that most commonly affects the lungs, lymphatic system, eyes, and skin. Cutaneous involvement is present in approximately 20-30% of patients. Prednisone and corticotropin repositories are the only FDA-approved therapies for sarcoidosis.
View Article and Find Full Text PDFJ Am Acad Dermatol
November 2024
Department of Dermatology, University of California Irvine, Irvine, California. Electronic address:
Respir Med
November 2024
Division of Pulmonary and Critical Care Medicine, Susan Pearlstine Sarcoidosis Center of Excellence, Medical University of South Carolina, Charleston, SC, USA. Electronic address:
As a multi system granulomatous disease, clinical presentations of sarcoidosis are highly variable. In the absence of a stereotypical clinical presentation such as asymptomatic bilateral hilar adenopathy, Lofgren's syndrome, or lupus pernio, a diagnosis of sarcoidosis typically requires 1) compatible clinical presentation, 2) histologic evidence of granulomatous inflammation, and 3) the exclusion of other causes. The clinical presentation of sarcoidosis is often nonspecific and a variety of other causes of granulomatous inflammation can make diagnosing sarcoidosis a challenge for clinicians.
View Article and Find Full Text PDFJAAD Case Rep
September 2024
Division of Rheumatology, University of Illinois College of Medicine, Chicago, Illinois.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!