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Identification of a sorting motif for Tspan3 to MHCII compartments in human B cells.
Biochim Biophys Acta Biomembr
December 2024
Department of Medical BioSciences, Radboud University Medical Center, Radboud Institute for Medical Innovation, Nijmegen, the Netherlands. Electronic address:
Tetraspanins are four-transmembrane proteins that play fundamental roles in the immune system by enabling processes like migration, proliferation, signaling and protein trafficking. While the importance of cell surface tetraspanins has been established, the function of intracellular tetraspanins is less well understood. Here, we investigated the role of tetraspanin 3 (Tspan3) in lymphocytes.
View Article and Find Full Text PDFCerebral arterial air embolism after esophageal stenting for recurrence of gastroesophageal junction cancer: a case report.
Int Cancer Conf J
October 2024
Department of Surgery, IGA City General Hospital, 831 Shijuku-cho, Iga, Mie 518-0823 Japan.
Article Synopsis
- * A case is reported of a 71-year-old man with recurrent gastroesophageal junction cancer who developed CAE after stenting, presenting with severe neurological symptoms and a confirmed diagnosis via CT scans.
- * Despite efforts to treat him, the patient unfortunately died shortly after showing signs of CAE, highlighting the increased risk of such complications in patients with extensive cancer treatment histories.
Isolated spermatic cord metastasis of prostate cancer after radiotherapy detected with F-PSMA PET/CT: a case report and literature review.
Int Cancer Conf J
October 2024
Division of Nuclear Medicine, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Article Synopsis
- * Imaging with F-PSMA PET/CT revealed a cancerous lesion in the left spermatic cord, which was confirmed as prostatic adenocarcinoma after surgery.
- * The exact cause of the metastasis is unclear, but potential pathways include intraluminal, hematogenous, and lymphatic routes; the case emphasizes the effectiveness of F-PSMA PET/CT in identifying cancer recurrence in unusual locations, even with low PSA levels.
EMVision: An electromagnetic tracking guidance system for accurate placement of interstitial brachytherapy applicators.
Brachytherapy
November 2024
Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905.
Article Synopsis
- The study aimed to create and assess EMVision, a system utilizing electromagnetic tracking technology to enhance the placement of brachytherapy applicators, focusing on procedure quality and efficiency.
- EMVision integrates CT imaging and EMT reference frames for precise needle placement, using an automated system that displays real-time 3D visuals and adjusts for anatomy shifts during the procedure.
- Results showed EMVision achieved high accuracy in needle placement, both in phantom tests and human cadaver evaluations, suggesting its potential to streamline brachytherapy procedures and improve training outcomes.
Commissioning considerations for the Bravos high-dose-rate afterloader: Towards improving treatment delivery accuracy.
Brachytherapy
November 2024
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY.
Background And Purpose: The upgrade of major equipment can be disruptive to clinical operations and introduce risk as policy and procedures need to adapt to new technical possibilities and constraints. We describe here the transition from GammaMedPlus-iX to Bravos in a busy brachytherapy clinic, involving four afterloaders across two sites.
Material And Methods: Our clinic employs three high-dose-rate remote afterloaders in four dedicated treatment vaults at the main site and a fourth afterloader at a regional location.
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