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The effect of epilepsy surgery on tonic-clonic seizures.
Epilepsia
January 2025
Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Objective: Epilepsy surgery outcomes tend to be judged by the percentage in seizure reduction without considering the effect on specific seizure types, particularly tonic-clonic seizures, which produce the greatest morbidity and mortality. We assess how often focal to bilateral tonic-clonic seizures (BTCS) stop and how often they appear de novo after epilepsy surgery.
Methods: Analysis of a prospectively maintained epilepsy surgery database between 1986 and 2022 that characterizes the burden of BTCS after resective epilepsy surgery.
Death Penalty in Modern Japan (1868-1945): Evolving Execution Practices and Their Societal Impact.
Omega (Westport)
January 2025
School of Law, Fu Jen Catholic University, New Taipei City, Taiwan.
This article investigates the evolution of capital executions in modern Japan, focusing primarily on two major aspects: the reform of execution methods to reduce physical suffering, and the implementation of measures to preserve the confidentiality of executions. These aspects created a notable distance between public awareness and the realities of death penalty, particularly regarding actual executions. Consequently, calls for abolition gradually shifted from concerns about the suffering of death-row inmates to societal issues and abstract theoretical considerations.
View Article and Find Full Text PDFPacific Peoples' Experiences of Cancer and Its Treatment in Aotearoa New Zealand Through Talanoa: A Qualitative Study of Samoan and Tongan Participants.
JCO Glob Oncol
January 2025
Auckland Regional Cancer and Blood Service, Te Toka Tumai Auckland, Health New Zealand, Te Whatu Ora, Auckland, New Zealand.
Article Synopsis
- The study examines the experiences of Pacific peoples in Aotearoa New Zealand with cancer treatment, focusing on the disparities they face compared to other ethnic groups.
- Data were collected through interviews with Samoan and Tongan patients, revealing five significant themes: perceptions of cancer, the need for holistic support, importance of communication and trust, financial barriers to care, and the need for better representation in healthcare.
- The findings emphasize the necessity for improved oncology care models that address the unique cultural and systemic challenges faced by Pacific communities to enhance access and support.
Basic Science and Pathogenesis.
Alzheimers Dement
December 2024
University of Miami, Miami, FL, USA.
Background: The global ageing population is rising with each year, and with that, the percentage of individuals with Alzheimer's disease (AD) is expected to rise in parallel. Along with age, traumatic brain injury (TBI) is another risk factor for AD. TBI and AD patients demonstrate abnormal inflammatory responses, including that of the inflammasome.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Centre for Brain Research, Indian Institute of Science, Bangalore, Karnataka, India.
Background: Dementia, a global health challenge, drives the need for comprehensive understanding. Longitudinal cohort studies are vital, yet maintaining follow-up in dementia cohorts poses challenges. This study explores challenges in follow-up, refines protocols, and develops strategies that can elevate dementia research quality.
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