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Smart home technology to support engagement in everyday activities while ageing: A focus group study with current and future generations of older adults.
PLoS One
January 2025
Faculty of Medicine, Department of Health Sciences, Lund University, Lund, Sweden.
Despite the potential of smart home technologies (SHT) to support everyday activities, the implementation rate of such technology in the homes of older adults remains low. The overall aim of this study was to explore factors involved in the decision-making process in adopting SHT among current and future generations of older adults. We also aimed to identify and understand barriers and facilitators that can better support older adults' engagement in everyday activities.
View Article and Find Full Text PDFCurrent state and promise of user-centered design to harness explainable AI in clinical decision-support systems for patients with CNS tumors.
Front Radiol
January 2025
Department of Biostatistics & Informatics, Colorado School of Public Health, Aurora, CO, United States.
In neuro-oncology, MR imaging is crucial for obtaining detailed brain images to identify neoplasms, plan treatment, guide surgical intervention, and monitor the tumor's response. Recent AI advances in neuroimaging have promising applications in neuro-oncology, including guiding clinical decisions and improving patient management. However, the lack of clarity on how AI arrives at predictions has hindered its clinical translation.
View Article and Find Full Text PDFI've really struggled but it does not seem to work: adolescents' experiences of living with ADHD - a thematic analysis.
BMC Psychol
January 2025
Department of Medical Sciences, Child and Adolescent Psychiatry, Uppsala University, Akademiska sjukhuset, ingång 10, plan, Uppsala, 751 85, Sweden.
Background: In Attention-deficit/hyperactivity disorder (ADHD) the transition from childhood to adolescence encompass changes in symptom manifestation and related challenges. Given the potential negative impact of ADHD on adolescents, and the increased risk for dropping out from treatment, there is a need to understand more about how adolescents experience their condition. The aim of this study was to explore adolescents' perceptions of how it is to live with ADHD.
View Article and Find Full Text PDFNIRS-BIDS: Brain Imaging Data Structure Extended to Near-Infrared Spectroscopy.
Sci Data
January 2025
Department of Engineering Technology, University of Houston, Houston, TX, USA.
Functional near-infrared spectroscopy (fNIRS) is an increasingly popular neuroimaging technique that measures cortical hemodynamic activity in a non-invasive and portable fashion. Although the fNIRS community has been successful in disseminating open-source processing tools and a standard file format (SNIRF), reproducible research and sharing of fNIRS data amongst researchers has been hindered by a lack of standards and clarity over how study data should be organized and stored. This problem is not new in neuroimaging, and it became evident years ago with the proliferation of publicly available neuroimaging datasets.
View Article and Find Full Text PDFLeveraging Saccharomyces cerevisiae for ADAR research: From high-yield purification to high-throughput screening and therapeutic applications.
Methods Enzymol
January 2025
Life Science, Bar Ilan University, Ramat Gan, Israel. Electronic address:
Saccharomyces cerevisiae, a model eukaryotic organism with a rich history in research and industry, has become a pivotal tool for studying Adenosine Deaminase Acting on RNA (ADAR) enzymes despite lacking these enzymes endogenously. This chapter reviews the diverse methodologies harnessed using yeast to elucidate ADAR structure and function, emphasizing its role in advancing our understanding of RNA editing. Initially, Saccharomyces cerevisiae was instrumental in the high-yield purification of ADARs, addressing challenges associated with enzyme stability and activity in other systems.
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