Marine Micromonospora was revealed to be a rather untapped and a rich source of chemically diverse and unique bioactive natural products. This review is aimed to make a comprehensive survey of secondary metabolites that were derived from marine Micromonospora including chemical diversity and biological activities. A total of 116 compounds from 41 marine Micromonospora species have been reported, covering the literatures from 1997 to 2019. These compounds contain several structural classes such as polyketides (PKS), nonribosomal peptides (NRPS), PKS-NRPS hybrids, terpenes and others, and they present cytotoxic, antibacterial, antiparasitic, chemopreventive or antioxidant activities.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/cbdv.202000024 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Biodegradation of oil-derived hydrocarbons by marine actinobacteria: A systematic review.
Environ Pollut
December 2024
Center of Natural Sciences and Technology., University of Pará State (UEPA), av. Eneas, 2626, Belém, Pará, Brazil.
The intensive use of oil and its derivatives is related to a greater frequency of accidents involving the release of pollutants that cause harmful effects on ecosystems. Actinobacteria are cosmopolitan and saprophytic microorganisms of great commercial interest, but because they are predominantly found in soil, most research into the products of this phylum's metabolism has focused on this habitat. Marine actinobacteria exhibit unique metabolic characteristics in response to extreme conditions in their habitat, which distinguishes them from terrestrial actinobacteria.
View Article and Find Full Text PDFBiodegradation of Di-2-Ethylhexyl Phthalate by Mangrove Sediment Microbiome Impacted by Chronic Plastic Waste.
Mar Biotechnol (NY)
December 2024
Department of Biology, Faculty of Science, Mahidol University, 272 Rama VI Road, Ratchathewi, Bangkok, 10400, Thailand.
Article Synopsis
- * Over a 35-day period, these microbiomes achieved a remarkable 99% reduction of DEHP, with specific bacterial groups identified as key contributors to the degradation process.
- * In addition, certain bacterial strains, like Gordonia sp. and Gordonia polyisoprenivorans, were found to degrade DEHP by 65-97% within just 7 days, showing potential for broader application in addressing plastic pollution.
Discovery of two new actinobacteria, Micromonospora palythoicola sp. nov. and Streptomyces poriticola sp. nov., isolated from marine invertebrates.
Sci Rep
September 2024
Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
Marine invertebrates represent an underexplored reservoir for actinobacteria, which are known to synthesize novel bioactive compounds. This study isolated 37 actinobacterial strains from five distinct marine invertebrate hosts, namely Chondrilla australiensis, Palythoa sp., Favia sp.
View Article and Find Full Text PDFGenome and Compound Analysis of Sioxanthin-Producing Marine Actinobacterium Micromonospora sp. nov. Strain SH-82 Isolated from Sponge Scopalina hapalia.
Curr Microbiol
August 2024
Chemistry and Biotechnology of Natural Products, CHEMBIOPRO, Université de La Réunion, Faculté des Sciences et Technologies, 15 Avenue René Cassin, 97744, Saint-Denis CEDEX 9, France.
Pigments and other secondary metabolites originating from marine microbes have been a promising natural colorants and drugs for multifaceted applications. However, marine actinobacteria producing such natural molecules are least investigated in terms of their taxonomy, chemical diversity and applications in biomedical, textile, and food industries. In this study, sioxanthin pigment-producing Gram-positive actinobacteria, Micromonospora sp.
View Article and Find Full Text PDFHeterologous Expression and Characterization of a pH-Stable Chitinase from with a Potential Application in Chitin Degradation.
Mar Drugs
June 2024
Hainan Engineering Research Center of Aquatic Resources Efficient Utilization in South China Sea, Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Key Laboratory of Seafood Processing of Haikou, National R&D Branch Center for Prawn Processing Technology (Haikou), School of Food Science and Engineering, Hainan University, Haikou 570228, China.
To promote the bioconversion of marine chitin waste into value-added products, we expressed a novel pH-stable -derived chitinase, Chi1, in and subsequently purified, characterized, and evaluated it for its chitin-converting capacity. Our results indicated that Chi1 is of the glycoside hydrolase (GH) family 18 with a molecular weight of approximately 57 kDa, consisting of a GH18 catalytic domain and a cellulose-binding domain. We recorded its optimal activity at pH 5.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!