Background: Nasal skin defect closures are challenging because the nose is a complex anatomic structure with several subunits, and the nasal tip and ala represent particularly difficult subunits to reconstruct. The traditional full-thickness skin graft (FTSG) is an easy and well-established method, but often results in undesirable outcomes in terms of the nasal contour caused by a lack of dermal tissue.
Aims: The purpose of the study is to report the outcomes of the simultaneous application of the acellular dermal substitute (Matriderm ) with FTSG in the treatment of nasal skin defects.
Patients/methods: Five patients with various nasal skin defects were treated with multilayered Matriderm grafts followed by FTSGs harvested from the pre- or postauricular region. Graft survival, scar quality, and patient satisfaction were evaluated and compared with 10 patients treated with conventional FTSGs.
Results: One-stage Matriderm-aided FTSGs were well-taken in all cases. Scar quality in the Matriderm group (8.0 ± 1.9) was statistically superior to that in the FTSG only group (10.8 ± 1.7). The Matriderm-aided graft was also superior in patient satisfaction.
Conclusions: The multilayered application of Matriderm in combination with FTSG is a reliable method for covering nasal skin defects, especially in the thick skin zone of the tip and ala.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/jocd.13342 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
First report of a cat (Felis catus) infected by Leishmania (Viannia) guyanensis from Southeastern Brazil.
Vet Res Commun
January 2025
René Rachou Institute - Osvaldo Cruz Foundation, Belo Horizonte, Minas Gerais, Brazil.
Feline leishmaniasis is increasingly recognized as a disease affecting cats worldwide, with notable prevalence in regions surrounding the Mediterranean Basin and in Brazil. An approximately one-year-old domestic shorthair cat was presented with small papules and nodules (2 mm) on the nasal planum. Physical examination and routine blood analyses were normal.
View Article and Find Full Text PDFCan 3 Stages Forehead Flap Provide Longer Flap Length?
J Craniofac Surg
November 2024
Private; Plastic Reconstructive and Aesthetic Surgery Clinic, Ankara, Turkey.
This article discusses the use of the forehead flap technique in nasal reconstruction, specifically examining the effect of the 3-stage forehead flap procedure in providing longer flap length. Traditionally performed in 2 stages, the forehead flap technique often requires additional operations due to the thickness of the forehead skin. The 3-stage procedure, however, allows for better control of the flap thickness and improved reconstruction of nasal subunits.
View Article and Find Full Text PDFKRT20-/SATB2+/MCPyV+ Sinonasal Merkel Cell Carcinoma: A Detailed Immunohistochemical and In Situ Hybridization Study.
Int J Surg Pathol
January 2025
Department of Pathology and Forensic Medicine, Ribeirão Preto Medical School (FMRP/USP), University of São Paulo, Ribeirão Preto, SP, Brazil.
Merkel cell carcinoma (MCC) is an uncommon aggressive neoplasm, usually arising in sun-exposed skin of the head and neck. By immunohistochemistry, KRT20 and MCPyV positivity are found in about 90% and 80% of MCCs, respectively. Noteworthy, viral status in lip/oral cavity MCCs is poorly known.
View Article and Find Full Text PDFSecrets revealed by the skin: initial success of tislelizumab and targeted therapy in advanced renal cell carcinoma-a case report and literature review.
Transl Androl Urol
December 2024
Department of Urology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Background: In renal cell carcinoma (RCC), skin metastases (SMs) occur in only 3.3% of cases and are even rarer as an initial manifestation of the disease. Although combination therapy with immune checkpoint inhibitors (ICIs) and targeted agents is the current standard of care, access to these treatments may be limited in certain regions due to cost constraints.
View Article and Find Full Text PDFPrimary-lobe-based trilobed and quadrilobed flaps for reconstruction of nasal tip skin defects.
JPRAS Open
March 2025
Department of Plastic and Craniofacial Surgery, MITERA Hospital, Hellenic Healthcare Group (HHG), 6 Erithrou Stavrou str., 151 23 Maroussi, Attica, Greece.
Background: Despite a variety of principles proposed for drawing trilobed and quadrilobed flaps for the reconstruction of nasal skin defects, the application of these principles in a detailed and reliable way remains questionable.
Methods: We present a novel method for drawing trilobed and quadrilobed flaps to cover nasal tip skin defects. The method is based on the use of templates corresponding to four trilobed flaps with overall angles of 60°, 70°, 80°, and 90°, and two quadrilobed flaps with angles of 90° and 105°.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!