Pharmacometric models simulation using NONMEM, Berkeley Madonna and R.

Transl Clin Pharmacol

Q-fitter Inc., 6th Floor, 412 Yeoksam-ro, Gangnam-gu, Seoul 06199, Korea.

Published: September 2017

In this tutorial, we introduce a differential equation simulation model for use in pharmacometrics involving NONMEM, Berkeley Madonna, and R. We report components of the simulation code and similarities/differences between software, rather than how to use each software. Depending on the purpose of the simulation, an appropriate tool can be selected for effective communication.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033377PMC
http://dx.doi.org/10.12793/tcp.2017.25.3.125DOI Listing

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