A new classification for congenital upper-extremity anomalies was first published in 2010. It has come to be known as the OMT classification highlighting the thought leaders behind it: Kerby Oberg, Paul Manske, and Michael Tonkin. Based on a dysmorphology framework, the OMT has been adopted by the International Federation of Society for Surgery of the Hand and surgeons who treat congenital upper-extremity anomalies. As predicted in the first publication, updates will be necessary based on an improved understanding of morphogenesis; the first update was in 2014 and this represents the second update to the original OMT classification. We carefully reviewed all aspects of the OMT classification, its current stratification, and updated literature on the developmental basis of limb anomalies. We also considered the clinical usefulness and challenges of the classification through discussions with stakeholders and those who care for patients with congenital upper-limb anomalies. These factors guided the current modifications of the OMT classification. In providing the updated classification, we provide the rationale for these changes. The updated OMT classification is by no means final. As our understanding of congenital anomalies progresses, we anticipate subsequent updates in the years to come.
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http://dx.doi.org/10.1016/j.jhsa.2020.01.002 | DOI Listing |
Zhongguo Zhong Yao Za Zhi
October 2024
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
Chrysanthemum morifolium is rich in hydroxyflavonoids and methoxyflavonoids(OMFs), and dissecting the biosynthetic pathway of OMFs in Ch. morifolium is of great theoretical and economic value because of the diverse physiological activities and pharmacological effects of OMFs. To investigate the biosynthetic pathway of OMFs in Ch.
View Article and Find Full Text PDFBMC Genomics
December 2024
State Key Laboratory of Aridland Crop Science/Agronomy College, Gansu Agricultural University, Lanzhou, 730070, China.
Background: O-Methyltransferase (OMTs) is a class of conserved multifunctional enzymes that play important roles in plant developmental regulation, hormone signaling, secondary metabolite synthesis and abiotic stress response. The GiOMT gene family has been identified and analyzed in species such as citrus, alfalfa, Populus and grape, but has not been reported in Glycyrrhiza inflata Bat.
Results: In this study, we systematically identified and analyzed the GiOMT gene family of G.
Rev Cardiovasc Med
November 2024
Divisionof Cardiology, University of Texas Medical Branch, Houston, TX 77555, USA.
Background: Spontaneous coronary artery dissection (SCAD) is a rare and often underdiagnosed cause of acute coronary syndrome (ACS), predominantly affecting younger women without traditional cardiovascular risk factors. The management of SCAD remains a subject of debate, likely secondary to inconclusive evidence. This study aims to compare the clinical outcomes of SCAD patients treated with optimal medical therapy (OMT) versus those who underwent percutaneous coronary intervention (PCI) using a national population-based cohort.
View Article and Find Full Text PDFCardiovasc Diagn Ther
October 2024
Department of Pediatric Cardiology, University Hospital for Pediatrics and Adolescent Medicine Ulm, Ulm, Germany.
Cardiovasc Diagn Ther
October 2024
Department of Pediatric Cardiology, University Hospital for Pediatrics and Adolescent Medicine Ulm, Ulm, Germany.
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