Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone implants based on hydroxyapatite modified with zinc ions. Zinc-modified hydroxyapatite was composed and synthesized. Using the XRD method, the phase composition was established. Using SEM, EPMA, and low-temperature nitrogen adsorption (BET) methods, surface properties were investigated. Antibacterial activity and biocompatibility have been established. The studied materials have antimicrobial activity; the samples did not cause significant changes in either the internal organs or the general condition of laboratory animals during the entire experiment.
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http://dx.doi.org/10.3390/jfb11010010 | DOI Listing |
J Funct Biomater
February 2020
Laboratory of Chemical Technology, National Research Tomsk State University, Lenin 36, 634050 Tomsk, Russia.
Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone implants based on hydroxyapatite modified with zinc ions. Zinc-modified hydroxyapatite was composed and synthesized.
View Article and Find Full Text PDFMater Sci Eng C Mater Biol Appl
May 2016
Bay Zoltán Nonprofit Ltd. for Applied Research, H-1116 Budapest, Fehérvári u. 130, Hungary.
In our research nanostructured silver and zinc doped calcium-phosphate (CaP) bioceramic coatings were prepared on commonly used orthopaedic implant materials (Ti6Al4V). The deposition process was carried out by the pulse current technique at 70 °C from electrolyte containing the appropriate amount of Ca(NO3)2 and NH4H2PO4 components. During the electrochemical deposition Ag(+) and Zn(2+) ions were introduced into the solution.
View Article and Find Full Text PDFHua Xi Kou Qiang Yi Xue Za Zhi
June 2008
State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
Objective: To prepare zinc-modified carbonated hydroxyapatite (Zn-CHA) coating material via sol-gel method and explore the influence of zinc substitution on physical and chemical properties of biomaterial samples.
Methods: Two kinds of samples with different zinc content and Ca/P molar ratio were prepared. One was fabricated with 4% zinc and the Ca/P molar ratio was 1.
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