The lens capsule, a thin specialized basement membrane that encloses the crystalline lens, is essential for both the structural and biomechanical integrity of the lens. Knowing the mechanical properties of the lens capsule is important for understanding its physiological functioning, role in accommodation, age-related changes, and for providing a better treatment of a cataract. In this review, we have described the techniques used for the lens capsule biomechanical testing on the macro- and microscale and summarized the current knowledge about its mechanical properties.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.jmbbm.2019.103600 | DOI Listing |
Int J Mol Sci
January 2025
NDDH, Royal Devon University Healthcare NHS Foundation Trust, Barnstaple EX31 4JB, UK.
Pseudoexfoliation syndrome (PXS) is an age-related fibrillopathy where fibrillar exfoliation material accumulates and deposits in ocular and extra-ocular tissue. Within the eye, this substance accumulates on the ocular surface and in the anterior segment of the eye, impacting ocular structures such as the conjunctiva, Tenon's capsule, sclera, cornea, iris, ciliary body, trabecular meshwork, and lens. This review aims to collate the current literature on how each anatomical part of the eye is affected by PXS, with a strong focus on molecular changes.
View Article and Find Full Text PDFBiomedicines
January 2025
Department of Ophthalmology, UHC Sestre Milosrdnice, 10000 Zagreb, Croatia.
We describe a novel experimental device, the VaMa (Vatavuk and Marić) artificial intraocular lens (IOL) capsule, and a method that enables all IOL types to be implanted in the bag. We present the application of the device and the procedure in patients with aphakia and native capsule damage and without efficient capsular support. The VaMa device and the method facilitate IOL exchange due to refractive errors and, in the case of their invention, the implementation of superior IOLs in the future.
View Article and Find Full Text PDFBMC Ophthalmol
January 2025
Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Purpose: Proliferative vitreoretinopathy (PVR) is a complication of retinal detachment which requires multiple vitreoretinal surgical interventions and frequent use of oil endotamponade. In this study, we conducted an in-depth analysis of complications associated with the use of heavy silicone oil in the management of inferior PVR.
Methods: A retrospective cohort study of 20 eyes that underwent vitrectomy for inferior PVR with use of heavy silicone oil (Densiron 68) between March 2021 and October 2022 at Oxford Eye Hospital.
BMC Ophthalmol
January 2025
Eye Institute, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China.
Background: Human anterior lens capsules (ALCs) have great potential in the treatment of multiple eye diseases, including corneal ulcers, glaucoma, age-related macular degeneration and macular holes. ALCs are also regarded as promising scaffolds for various ocular cells. Here, we investigated different decellularization methods for removing lens epithelial cells (LECs) that adhered to ALCs.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
Zhuhai People's Hospital, Zhuhai, China.
Rationale: The double-layer sign of the anterior lens capsule during continuous curvilinear capsulorrhexis (CCC) in cataract surgery is a rare phenomenon. This case report highlights the occurrence of this sign and provides a practical technique for managing it.
Patient Concerns: A 55-year-old Chinese woman presented with blurred vision in her left eye.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!