Objective: To evaluate the feasibility and safety of portal vein stenting (PVS) combined with I particle chain implantation and sequential arsenic trioxide (AsO) for the treatment of hepatocellular carcinoma (HCC) with portal vein tumour thrombus (PVTT) by transcatheter arterial chemoembolization (TACE).
Methods: From January 2015 to January 2018, the clinical data of 30 patients with HCC complicated by PVTT were retrospectively analysed (26 men and 4 women). The laboratory examinations, incidence of adverse events, cumulative survival rate, and stent patency were analysed for all enrolled patients.
Results: The success rate of interventional treatment in all patients was 100%. The results of the laboratory tests before and 1 week after surgery showed that the mean concentrations of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) decreased from 50.9 U/L ± 25.8 to 41.8 U/L ± 21.6 ( < 0.001) and 57.6 U/L ± 19.9 to 44.2 U/L ± 26.1 ( < 0.001) and 57.6 U/L ± 19.9 to 44.2 U/L ± 26.1 (.
Conclusion: PVS combined with I particle chain implantation followed by TACE with AsO is safe and feasible for patients with PVTT. The long-term efficacy of this treatment needs to be further studied.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013352 | PMC |
| http://dx.doi.org/10.1155/2020/4109216 | DOI Listing |
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