Objective: The aim of this study was to evaluate objective limb function using force plate gait analysis after tibial plateau levelling osteotomy (TPLO) in small breed dogs with cranial cruciate ligament rupture (CCLR).
Materials And Methods: Small breed dogs (15 kg or less) with unilateral CCLR treated with TPLO were evaluated using symmetry index (SI) of peak vertical force (PVF), vertical impulse and vector magnitude at PVF performed preoperatively and at 1, 2, 4 and 6 months postoperatively after routine TPLO surgery.
Results: Twelve dogs met the inclusion criteria. Hindlimb function was markedly improved after TPLO, with all three postoperative SI significantly higher after a month than preoperative values ( < 0.01). At 2 months after surgery, the SI was nearly normalized to 1.0 (preoperative SI: 0.50 ± 0.20, 0.44 ± 0.19 and 0.51 ± 0.19, and 2 months postoperative SI: 0.92 ± 0.16, 0.90 ± 0.18 and 0.92 ± 0.16 respectively). Complications were noted in two dogs (fibular fracture and a partial implant failure), neither of which required a revision surgery for acceptable functional recovery.
Conclusion: The objective limb function of the affected hindlimb improved continuously after surgery and reached a near normal value at 6 months after surgery. It was suggested that TPLO for small breed dogs had good outcomes based on force plate gait analysis.
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http://dx.doi.org/10.1055/s-0039-1700990 | DOI Listing |
Vet Q
December 2025
Department of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, Canada.
This review examines the role of the canine blood-brain barrier (BBB) in health and disease, focusing on the impact of the multidrug resistance (MDR) transporter P-glycoprotein (P-gp) encoded by the gene. The BBB is critical in maintaining central nervous system homeostasis and brain protection against xenobiotics and environmental drugs that may be circulating in the blood stream. We revise key anatomical, histological and functional aspects of the canine BBB and examine the role of the gene mutation in specific dog breeds that exhibit reduced P-gp activity and disrupted drug brain pharmacokinetics.
View Article and Find Full Text PDFVet Res Commun
January 2025
Department of Biomaterials and Medical Devices Engineering, Faculty of Biomedical Engineering, Silesian University of Technology, Roosevelta 40, Zabrze, 41-800, Poland.
Chronic instability at the lumbosacral junction, particularly between the L7 vertebra and the sacral bone, presents significant challenges in veterinary orthopedics, especially for large breed dogs. This condition frequently results in severe pain, neurological deficits, and mobility impairments, prompting the development of various surgical techniques aimed at effectively stabilizing the affected area. A critical evaluation of the literature on surgical stabilization of the lumbosacral spine in dogs reveals the clinical applications, outcomes, and future directions in veterinary spinal surgery.
View Article and Find Full Text PDFJ Vet Diagn Invest
January 2025
Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA.
A 9-y-old, spayed female, non-brachycephalic mixed-breed dog was presented with progressive abdominal distension and diarrhea of <24 h duration. An echocardiogram revealed nodular masses in the pericardium and myocardium, particularly near the auricles. Diagnostic and therapeutic pericardiocentesis failed to improve the dog's status, and the owner elected euthanasia.
View Article and Find Full Text PDFPathogens
December 2024
Centro di Referenza Nazionale per Anaplasma, Babesia Rickettsia, e Theileria (C.R.A.Ba.R.T.), Istituto Zooprofilattico Sperimentale della Sicilia "A. Mirri", 90129 Palermo, Italy.
Vector-borne diseases represent a serious threat to human and animal health, especially where environmental conditions favor pathogen-carrying vectors. Dogs serve as natural hosts for two tick-borne pathogens: , which causes canine monocytic ehrlichiosis, and spotted fever group (SFG) spp., a zoonotic threat in the Mediterranean region.
View Article and Find Full Text PDFPathogens
December 2024
Department of Parasitology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, 40-055 Katowice, Poland.
is the parasite responsible for a life-threatening disease for dogs in Central Europe, of which the main vector is the ornate dog tick-. The objective of the presented study was to assess the prevalence of infection in dogs with clinical suspicion of babesiosis, which tested positive for from locations where there is no or very limited information about dog exposure to this pathogen. In order to confirm the presence of this protozoan, blood samples were collected from dogs treated in veterinary clinics with suspicion of canine babesiosis.
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