Non-tuberculous mycobacterial infection has increased significantly in recent years, especially in emerging countries. We present the case of a 25-year-old male patient, immunocompetent, with cervical lymphadenopathy, identifying Mycobacterium kumamotonense, a rare species in extrapulmonary forms and with a high drug resistance index.
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http://dx.doi.org/10.3855/jidc.11935 | DOI Listing |
Indian J Med Microbiol
December 2024
Department of Respiratory Medicine, Shizuoka City Shizuoka Hospital, 10-93, Ohte-machi, Aoi-ku, Shizuoka City, Shizuoka, 420-8630, Japan. Electronic address:
Herein, we report a rare case of pulmonary nontuberculous mycobacterial (NTM) infection caused by Mycolicibacter kumamotonensis in a 73-year-old man successfully treated with clarithromycin, rifampicin, and ethambutol. Seven cases of NTM disease caused by M. kumamotonensis have been previously described, with characteristics differing from those of more common NTM diseases.
View Article and Find Full Text PDFGenes (Basel)
April 2023
Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional (IPN), Prolongación de Carpio y Plan de Ayala S/N, Colonia Santo Tomas, Delegación Miguel Hidalgo, Ciudad de México 11340, Mexico.
The slow-growing, nontuberculous mycobacterium possesses two rRNA operons, and , located downstream from the and genes, respectively. Here, we report the sequence and organization of the promoter regions of these two operons. In the operon, transcription can be initiated from the two promoters, named P1 and PCL1, while in , transcription can only start from one, called P1 .
View Article and Find Full Text PDFBMC Infect Dis
January 2023
Department of Pathology and Cell Biology, Columbia University Irving Medical Center, 3959 Broadway, CHC 3-324, New York, NY, 10032, USA.
Introduction: Mycolicibacter kumamotonensis is a slowly growing, non-chromogenic non-tuberculous mycobacteria (NTM) that was initially distinguished from the M. terrae complex in 2006. Since then it has been rarely reported as the cause of pulmonary and soft-tissue infections in both immunocompromised and immunocompetent patients.
View Article and Find Full Text PDFJRSM Open
October 2022
Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, UK.
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