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Validation of Muscle Ultrasound Speckle Tracking and the Effect of Nordic Hamstring Exercise on Biceps Femoris Displacement.
Ultrasound Med Biol
January 2025
School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan ROC; Center of Physical Therapy, National Taiwan University Hospital, Taipei, Taiwan ROC. Electronic address:
Objective: This study aimed to validate the ultrasound speckle tracking (UST) algorithm, determine the optimal probe location by comparing normalized cross-correlation (NCC) values of muscle displacement at two locations (proximal vs. middle) of the biceps femoris long head (BFlh) using the UST, and investigate the effects of Nordic hamstring curl exercise (NHE) training on BFlh displacement.
Methods: UST efficacy was verified with ex vivo uniaxial testing of porcine leg muscles.
Low-Complexity Timing Correction Methods for Heart Rate Estimation Using Remote Photoplethysmography.
Sensors (Basel)
January 2025
Department of Biomedical and Robotics Engineering, Incheon National University, Incheon 22012, Republic of Korea.
With the rise of modern healthcare monitoring, heart rate (HR) estimation using remote photoplethysmography (rPPG) has gained attention for its non-contact, continuous tracking capabilities. However, most HR estimation methods rely on stable, fixed sampling intervals, while practical image capture often involves irregular frame rates and missing data, leading to inaccuracies in HR measurements. This study addresses these issues by introducing low-complexity timing correction methods, including linear, cubic, and filter interpolation, to improve HR estimation from rPPG signals under conditions of irregular sampling and data loss.
View Article and Find Full Text PDFA simple, economical, and high-yield method for polyethylene glycol-based extraction of follicular and serum-derived extracellular vesicles.
Tzu Chi Med J
October 2024
Center for Prevention and Therapy of Gynecological Cancers, Department of Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Objectives: The optimization of polyethylene glycol (PEG)-based extracellular vesicles (EVs) extraction from human follicular fluid (FF) and serum was investigated, and their functional analysis was confirmed. The PEG-based EV results were compared to the ExoQuick (ExoQ)-based EV.
Materials And Methods: FF-EVs and serum-EVs were extracted by using different concentrations of PEG (8000).
Disrupted microsaccade responses in late-life depression.
Sci Rep
January 2025
Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei City, Taiwan.
Late-life depression (LLD) is a psychiatric disorder in older adults, characterized by high prevalence and significant mortality rates. Thus, it is imperative to develop objective and cost-effective methods for detecting LLD. Individuals with depression often exhibit disrupted levels of arousal, and microsaccades, as a type of fixational eye movement that can be measured non-invasively, are known to be modulated by arousal.
View Article and Find Full Text PDFLight sheet fluorescence microscopy for monitoring drug delivery: Unlocking the developmental phases of embryos.
Adv Drug Deliv Rev
January 2025
Light sheet fluorescence microscopy (LSFM) has emerged as a transformative imaging technique in the study of drug delivery and embryonic development, offering high-resolution, real-time visualization with minimal phototoxicity. This review examines the application of LSFM in tracking drug pharmacokinetics, tissue-specific targeting, and drug efficacy during critical phases of embryonic development. Recent advancements in fluorescent labeling and machine learning integration have enabled more precise monitoring of drug release, distribution, and interaction with developing tissues.
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