AI Article Synopsis
- Tumour partial oxygen pressure (PO2) decreases by 2-3 times during a glucose infusion lasting 120-150 minutes in rats with Guerin carcinoma.
- The decline in oxygen levels is linked to a reduction in oxygen transport to the tumour.
- This reduction is caused by an inhibition of local blood flow in the tumour region.
Article Abstract
It is shown that tumour PO2 falls by the factor of 2 or 3 at the 120-150 min i/v glucose infusion (80 mg.kg-1.min-1) to the rats bearing Guerin carcinoma. This is due to a decrease oxygen transport into the tumour induced by inhibition of local blood flow.
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