A 4-week-old female patient presented with severe respiratory distress, hypoxia and apnoeic episodes on a background of a few-day history of coryza and cough. There was significantly reduced air entry on the left side and a displacement of the apex beat to the right of the chest. The examination findings with oxygen desaturations and a right-sided mediastinal shift on chest X-ray led to a diagnosis of tension pneumothorax following which a needle thoracentesis was undertaken. This appeared to worsen the patient's clinical condition; hence, a chest drain was inserted with unsatisfactory clinical improvement. In view of the presentation and lack of clinical improvement after chest drain insertion, the case was transferred to the paediatric respiratory team in a tertiary centre where the diagnosis was revised to congenital lobar emphysema based on chest computer tomography findings. She subsequently benefited from a left upper lobectomy and lingulectomy and was discharged home 4 days after surgery.
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http://dx.doi.org/10.1136/bcr-2019-233302 | DOI Listing |
Cureus
November 2024
Neonatology, Souss Massa University Hospital Center, Agadir, MAR.
Holoprosencephaly (HPE) is a severe and complex congenital brain malformation caused by a defect in the midline cleavage of the prosencephalon during early embryonic development. It is the most common prosencephalic malformation in humans and is categorized into three classical forms based on the severity of this cleavage defect: alobar, semilobar, and lobar HPE. A milder interhemispheric variant, called syntelencephaly, is also considered a form of HPE.
View Article and Find Full Text PDFJ Neurodev Disord
December 2024
Carolina Institute for Developmental Disabilities (CIDD), University of North Carolina at Chapel Hill, 101, Renee Lynne Court, Carrboro, NC, 27510, USA.
Background: Down syndrome (DS) is the most common congenital neurodevelopmental disorder, present in about 1 in every 700 live births. Despite its prevalence, literature exploring the neurobiology underlying DS and how this neurobiology is related to behavior is limited. This study fills this gap by examining cortical volumes and behavioral correlates in school-age children with DS.
View Article and Find Full Text PDFPediatr Surg Int
December 2024
Neurofarba Department, University of Florence, Florence, Italy.
Aim Of The Study: Patients with congenital lung malformation (CLM) may present pulmonary inflammatory changes. However, little is known about the factors influencing local inflammation. The aim of this study was to evaluate the factors that may affect inflammatory changes in CLM.
View Article and Find Full Text PDFAm J Case Rep
December 2024
Department of Surgery, Faculty of Medicine, Al-Baha University, Al-Baha, Saudi Arabia.
BMJ Case Rep
November 2024
Radiology, Narayana Hrudayalaya Health City Bangalore, Bengaluru, Karnataka, India
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