DNAid is a full screen and multi-window sequence editor designed as an aid for the easy manipulation of DNA and protein sequences on Macintosh computers. In addition to the classical editing capabilities, powerful analysis and search functions are available from within the editor. Restriction mapping, translation and alignment of homologous sequences are supported by DNAid, furthermore a pattern matching language is included which allows searches for user-defined strict or fuzzy signals within biological sequences. Patterns are translated into finite state automata which allow very efficient searches.
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Low-dose Systemic Tissue-type-plasminogen-activator Compared to Conventional Anti-coagulation for the Treatment of Intermediate-high Risk Pulmonary Embolism.
Cardiovasc Hematol Disord Drug Targets
January 2025
Division of Pulmonary and Critical Care Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Background: Pulmonary embolism (PE) is a frequent cause of death. Acute PE may be treated either with full anticoagulation (AC) alone or thrombolytic therapy with systemic tissue-- type-plasminogen-activator (tPA) based on risk assessment. Currently, AC is the standard of care for most patients with intermediate-high-risk PE, with low-dose tPA emerging as an effective alternative.
View Article and Find Full Text PDFComplete Third Nerve Palsy With Pupil Involvement in Herpes Zoster Ophthalmicus: A Case Report.
Cureus
December 2024
Department of Ophthalmology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.
Simultaneous complete oculomotor nerve palsy in herpes zoster ophthalmicus (HZO) is rare. We report a case of a 65-year-old lady who presented with a right drooping eyelid for 2 days associated with rashes over her right forehead. Examination showed crusted vesicular lesions on the right V1 dermatome with right complete ptosis, anisocoria, and limited right extraocular movement on all gazes except full movement on abduction.
View Article and Find Full Text PDFBiologic Augmented Scaffold-based cartilage repair: Addressing Complications and Enhancing Outcomes.
J Clin Orthop Trauma
March 2025
Department of Orthopaedic Surgery, Sengkang General Hospital, Singapore.
Cartilage repair remains a significant challenge due to the tissue's limited innate regenerative capacity. Despite advances in techniques such as microfracture, autologous chondrocyte implantation (ACI), and osteochondral grafting, long-term outcomes are often compromised by complications, including suboptimal tissue integration, graft resorption, and mechanical instability. Recently, biologically augmented scaffold-based cartilage repair has emerged as a promising approach for full-thickness osteochondral lesions.
View Article and Find Full Text PDFStudy on the changes and influencing factors of depression in Chinese women with cancer: an analysis based on CHARLS panel data.
Front Public Health
January 2025
School of Languages and Media, Anhui University of Finance and Economics, Bengbu, China.
Background: The social problems caused by depressive disorders and psychological behaviors in women are increasingly prominent, with extreme incidents occurring from time to time. Therefore, the issue concerning "how to prevent and resolve the risk of depression in women" is gaining significant attention across various sectors. However, previous studies have largely focused on teenage girls, perimenopausal women, or women during pregnancy and the postpartum period, neglecting the adverse effects of major diseases, which is detrimental to enhancing the psychological well-being of women with cancer.
View Article and Find Full Text PDFConstructing Two-Dimensional, Ordered Networks of Carbon-Carbon Bonds with Precision.
Precis Chem
January 2025
Department of Chemical System Engineering, School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan.
Organic semiconducting nanomembranes (OSNMs), particularly carbon-based ones, are at the forefront of next-generation two-dimensional (2D) semiconductor research. These materials offer remarkable promise due to their diverse chemical properties and unique functionalities, paving the way for innovative applications across advanced semiconductor material sectors. Graphene stands out for its extraordinary mechanical strength, thermal conductivity, and superior charge transport capabilities, inspiring extensive research into other 2D carbon allotropes like graphyne and graphdiyne.
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