AI Article Synopsis
- Shenmai injection (SMI) is a Traditional Chinese Medicine made from ophiopogonis radix and ginseng radix rubra, showing promise in improving treatment outcomes for dilated cardiomyopathy (DCM) when used alongside conventional medicine.
- A systematic review and meta-analysis is planned to collect and evaluate data from various medical databases to validate SMI's effectiveness as a treatment for DCM.
- The study aims to provide comprehensive, high-quality evidence supporting the use of SMI as an adjunct treatment for DCM patients.
Article Abstract
Background: Shenmai injection (SMI) is a Traditional Chinese Medicine patent prescription consisting of extractions from ophiopogonis radix and ginseng radix rubra. Clinical studies showed that SMI combined with conventional medicine treatment (CMT) can enhance the therapeutic efficacy for dilated cardiomyopathy (DCM). However, there is still a lack of comprehensive and systematic evidence, which urgently requires us to verify its therapeutic efficacy. Hence, we provide a protocol for systematic review and meta-analysis.
Methods: The systematic search on the MEDLINE/PubMed, China National Knowledge Infrastructure (CNKI), Wanfang database, VIP database, the Cochrane Library, Embase and Chinese Biomedical Database (CBM) in Chinese and English language with dates ranging from the earliest record to August 8, 2019. Next, the quality of each trial was assessed according to the criteria of the Cochrane Handbook for Systematic Reviews of Interventions. Then, the outcome data were recorded and pooled by RevMan 5.3 software.
Results: The systematic review and meta-analysis aims to review and pool current clinical outcomes of SMI for the adjuvant treatment of DCM.
Conclusion: This study will provide a high-quality evidence of SMI for the adjuvant treatment on DCM patients.
Prospero Registration Number: CRD42019146369.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034733 | PMC |
| http://dx.doi.org/10.1097/MD.0000000000019158 | DOI Listing |
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