Objective: Investigate if there is an association between apical periodontitis and diabetes mellitus.
Material And Methods: A bibliographic search was performed on Medline/PubMed, Scopus and Cochrane databases using the keywords apical periodontitis and diabetes mellitus. Published papers written in English and performed on animals or humans were included. Meta-analysis was performed using the OpenMeta (analyst) tool for the statistical analysis. The variables analyzed were the prevalence of Apical Periodontitis (AP) among teeth and patients with Diabetes Mellitus (DM).
Results: Of the total studies found, only 21 met the inclusion criteria. Ten clinical studies on animals, ten studies on humans and a systematic review were included. Meta-analysis shows that the prevalence of teeth with apical periodontitis among patients with diabetes mellitus has an odds ratio of 1.166 corresponding to 507 teeth with AP + DM and 534 teeth with AP without DM. The prevalence of patients with AP and DM shows an odds ratio of 1.552 where 91 patients had AP + DM and 582 patients AP without DM.
Conclusion: Scientific evidence suggests that there could be a common physiopathological factor between apical periodontitis and diabetes mellitus but more prospective studies are needed to investigate the association between these two diseases.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074097 | PMC |
| http://dx.doi.org/10.3390/jcm9020540 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluation of dentists' clinical practices and antibiotic use in managing endodontic emergencies in Karachi, Pakistan: a cross-sectional survey.
BMC Oral Health
December 2024
Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
Background: Endodontic emergencies, often presented as acute pain or swelling, constitute a substantial challenge in dental practice. While effective management emphasizes prompt intervention, antibiotics are typically indicated only when systemic signs and symptoms are present. There is limited research exists on evaluating the knowledge and clinical approach of dental practitioners in managing endodontic emergencies from our region of the world.
View Article and Find Full Text PDFClinical and Radiographic Parameters for Early Periodontitis Diagnosis: A Comparative Study.
Dent J (Basel)
December 2024
School of Electrical Engineering and Computer Science, University of Queensland, St. Lucia 4072, Australia.
Early periodontitis diagnosis is challenging due to varying staging and grading systems. While clinical parameters like bleeding on probing (BoP) and pocket depth (PD) are commonly used, periapical radiographs provide valuable information about bone loss and periodontal ligament changes. However, a clear definition of early periodontitis, particularly regarding alveolar bone crest changes, remains elusive.
View Article and Find Full Text PDFPost-COVID-19 Trends in Dental Emergencies: A Two-Year Retrospective Study from Romania.
Dent J (Basel)
December 2024
Department of Dentistry, Faculty of Medicine and Pharmacy, University of Oradea, 10 Piața 1 Decembrie Street, 410073 Oradea, Romania.
: Dental emergencies significantly impact public oral health, particularly in the post-COVID-19 context. This study aimed to analyze the patterns of dental emergencies presenting to the Emergency Dental Service in Bihor, Romania, during the years 2022 and 2023, focusing on demographic characteristics and the frequency of diagnoses. : A retrospective analysis of medical records from the Emergency Dental Service at Oradea County Emergency Clinical Hospital was conducted.
View Article and Find Full Text PDFA considerable portion of the global population is affected by pulpitis and periapical lesions. While the impact of infections caused by various microbes and host effector molecules in pulpal and periapical diseases is widely recognized, disease susceptibility and progression are also influenced by the dynamic interaction between host genetic factors and environmental influences. Apical periodontitis occurs as an inflammatory response to microorganisms present in the root canals of infected teeth.
View Article and Find Full Text PDFImpact of type 2 diabetes mellitus on the prevalence of apical periodontitis in endodontically treated and untreated teeth.
J Med Life
October 2024
Department of Doctoral Sciences, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
Apical periodontitis (AP) is a common dental condition that can be influenced by diabetes mellitus. This study aimed to investigate the impact of type 2 diabetes mellitus (T2DM) on the prevalence and severity of AP, considering the adequacy of endodontic treatments. A total of 180 patients selected based on specific dental criteria from a private clinic in Oradea, Romania, were included in this study.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!