High-resolution 31P-NMR is used for the estimation of phosphate-containing compounds levels in native bile of healthy subjects and patients with primary biliary liver cirrhosis and also in the liver biopsies of patients with chronic calculous cholecystitis. The results demonstrate the possibilities of rapid comparative estimation of the content of main phosphate-containing compounds in human bile and liver biopsies aimed at clinical diagnosis of liver and bile duct diseases.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Mimicking the Bone Extracellular Matrix through a Calcium Phosphate-Containing Thiol-Ene Cross-Linked Gelatin Composite.
Biomacromolecules
January 2025
Polymer Chemistry and Biomaterials (PBM) Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Faculty of Sciences, Ghent University, Krijgslaan 281, Building S4, Ghent 9000, Belgium.
Hydroxyapatite (HAP) and amorphous calcium phosphate (ACP) nanoparticles were incorporated into a thiol-ene clickable gelatin network to elucidate to what extent osteogenic differentiation of human dental pulp- and adipose-derived stem cells (HDPSCs/HASCs) could be further boosted. ACP nanoparticles increased the specific surface area by 23% and reduced the density by 13% while maintaining a comparable particle size (ACP: 25 ± 3 nm; HAP: 27 ± 3 nm). Overall, the incorporation of ceramic nanoparticles did not significantly alter the mechanical properties of the ceramic-containing composites compared to the unsubstituted thiol-ene network.
View Article and Find Full Text PDFMolecular Selectivity of a pH-Tunable Lecithin-Modified Zirconia Stationary Phase.
ACS Omega
November 2024
Graduate School of Science and Technology, Kochi University, 2-5-1 Akebono, Kochi 780-8520, Japan.
We synthesized lecithin-modified zirconia (LMZ) as an adsorbent, solid-phase extractant, and stationary phase for organic compounds such as organic acids or amino acids. The molecular selectivity of LMZ was evaluated through high-performance liquid chromatography (HPLC). LMZ exhibits electrostatic and hydrophobic interactions with organic compounds that depend on the pH of the mobile phase.
View Article and Find Full Text PDFDelivery system for dexamethasone phosphate based on a Zn-crosslinked polyelectrolyte complex of diethylaminoethyl chitosan and chondroitin sulfate.
Carbohydr Polym
January 2025
Institute of Macromolecular Compounds, Branch of Petersburg Nuclear Physics Institute named by B.P. Konstantinov, National Research Centre «Kurchatov Institute», Bolshoi VO 31, St. Petersburg 199004, Russia. Electronic address:
Hybrid nano- and microparticles based on metal ion crosslinked biopolymers are promising carriers for the development of drug delivery systems with improved biopharmaceutical properties. In this work, dexamethasone phosphate-containing particles based on chondroitin sulfate and chitosan or diethylaminoethyl chitosan additionally crosslinked with Zn were prepared. Depending on the polycation/polyanion ratio in the system, anionic and cationic polyelectrolyte complexes (PECs) were obtained.
View Article and Find Full Text PDFEnhancement of the Plant-Accessible Phosphate Fraction in Sewage Sludge Ashes by Na or K Addition Prior to Combustion.
ChemSusChem
November 2024
Institute for Inorganic and Analytical Chemistry (IAAC) / Freiburg Materials Research Center (FMF), University of Freiburg, Albertstraße 21, 79104, Freiburg, Germany.
With the aim of transforming sewage sludge into a P-fertiliser material in a single combustion step, the chemical processes underlying sewage sludge combustion were analysed using powder X-ray diffraction (P-XRD), infrared spectroscopy (IR), thermogravimetric (TGA) as well as elemental analyses (EA). In addition to the combustion of sewage sludge on its own ("mono-combustion"), additions of different additives prior to the combustion step were also carried out. Based on the very positive effects of the additives sodium and potassium carbonate on the obtained ashes concerning their phosphate solubilities in neutral ammonium citrate (NAC) solution, sewage sludge combustions after additions of NaCO or KCO were investigated in detail.
View Article and Find Full Text PDFBiobased Sulfur- and Phosphate-Containing High-Refractive-Index Polymers: Substituent Effects on Optical Properties of Polymers.
Biomacromolecules
December 2024
Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, P. R. China.
Four biobased phosphate-containing aryl monomers with methoxy, allyl, and vinyl groups as substituents have been successfully synthesized. Copolymerizing these monomers with thiophenol or mercaptans via the photoclick thiol-ene reaction gives the polymers with refractive indices () of 1.63-1.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!