Conventional classification models for epileptic EEG signal recognition need sufficient labeled samples as training dataset. In addition, when training and testing EEG signal samples are collected from different distributions, for example, due to differences in patient groups or acquisition devices, such methods generally cannot perform well. In this paper, a cross-domain classification model with knowledge utilization maximization called CDC-KUM is presented, which takes advantage of the data global structure provided by the labeled samples in the related domain and unlabeled samples in the current domain. Through mapping the data into kernel space, the pairwise constraint regularization term is combined together the predictive differences of the labeled data in the source domain. Meanwhile, the soft clustering regularization term using quadratic weights and Gini-Simpson diversity is applied to exploit the distribution information of unlabeled data in the target domain. Experimental results show that CDC-KUM model outperformed several traditional non-transfer and transfer classification methods for recognition of epileptic EEG signals.
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http://dx.doi.org/10.1109/TCBB.2020.2973978 | DOI Listing |
Epilepsia Open
December 2024
Department of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Objective: To analyze the clinical characteristics, etiology, drug treatment, and related factors of patients with young adult-onset epilepsy.
Methods: The study included patients with epilepsy aged between 18 and 44 years and aimed to analyze the clinical characteristics of epilepsy in young people and their response to antiseizure medication (ASM) over a 24-year period (February 1999 and March 2023).
Results: A total of 4227 patients experienced epilepsy onset between 18 and 44 years of age.
Virtual Real
December 2024
Department of Computer Science and Software Engineering, Concordia University, Montreal, Québec Canada.
Epilepsy is a neurological disorder characterized by recurring seizures that can cause a wide range of symptoms. Stereo-electroencephalography (SEEG) is a diagnostic procedure where multiple electrodes are stereotactically implanted within predefined brain regions to identify the seizure onset zone, which needs to be surgically removed or disconnected to achieve remission of focal epilepsy. This procedure is complex and challenging due to two main reasons.
View Article and Find Full Text PDFTher Adv Neurol Disord
December 2024
Department of Neurology, Fujian Medical University Union Hospital, Xinquan Road 29#, Fuzhou 350001, China.
Background: Drug-resistant epilepsy (DRE) patients exhibit aberrant large-scale brain networks.
Objective: The purpose of investigation is to explore the differences in resting-state electroencephalogram (EEG) microstates between patients with DRE and well-controlled (W-C) epilepsy.
Design: Retrospective study.
Cureus
November 2024
Department of Epileptology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, JPN.
Herein, we present a case of idiopathic generalized epilepsy (IGE) manifesting as de novo late-onset absence status epilepticus (ASE) following mild coronavirus disease 2019 (COVID-19). A woman in her 40s presented with persistent 3-5.5 Hz generalized spike-wave complexes (SWCs) on electroencephalography (EEG).
View Article and Find Full Text PDFNeuroimage
December 2024
Hospital del Mar Research Institute; 08003 Barcelona, Spain; Universitat Pompeu Fabra; 08003 Barcelona, Spain; Epilepsy Unit - Neurology Dept. Hospital del Mar; 08003 Barcelona, Spain.
The rate of success of epilepsy surgery, ensuring seizure-freedom, is limited by the lack of epileptogenicity biomarkers. Previous evidence supports the critical role of functional connectivity during seizure generation to characterize the epileptogenic network (EN). However, EN dynamics is highly variable across patients, hindering the development of diagnostic biomarkers.
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