A fast, effective, and safe disinfection of personal protective equipment (PPE) is vitally important for emergency forces involved in biological hazards. This study aimed to investigate a broad range of disinfectants to improve the established disinfection procedure. We analyzed the efficacy of chlorine-, peracetic acid-, and oxygen-based disinfectants against spores on PPE. Therefore, spores of different species were exposed to disinfectants on PPE material by using a standardized procedure covering the dried spores with disinfectants and applying mechanical distribution. Efficacy of disinfectants was quantified by determining the reduction factor (log levels) and number of viable spores left afterward. The chlorine-based granulate Hypochlorit CA G (2% chlorine) sufficiently inactivated spores of risk groups 1 and 2, even with temperatures ranging from -20 to 35°C. Wofasteril SC super (1.75% peracetic acid) achieved a reliable reduction of risk groups 1 and 2 and even fully virulent spores by ≥5 log levels on PPE. With this, Hypochlorit-CA G and Wofasteril SC super proved to be promising alternatives to the previously proven and widely used peracetic acid compound Wofasteril (2% peracetic acid) for the disinfection of PPE when bacterial spores are known to be the contaminating agent. These results will help to improve the disinfection of PPE during biological hazards by providing new data on promising alternative compounds.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047094 | PMC |
http://dx.doi.org/10.1089/hs.2019.0128 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!