AI Article Synopsis
- - A multicenter study conducted across 10 oral and maxillofacial pathology centers in Brazil analyzed over 198,000 biopsy specimens from 1953 to 2018 to assess the occurrence of actinic cheilitis (AC) and lip squamous cell carcinoma (LSCC).
- - In total, the study identified 2017 cases of AC (1.0%) and 850 cases of LSCC (0.4%), showing a notable prevalence among fair-skinned males, with the lower lip being the most affected area (over 90%).
- - This research aligns with global findings on the frequency and characteristics of AC and LSCC, providing valuable and comprehensive epidemiological data for the scientific community.
Article Abstract
Data on the occurrence and clinicopathological characteristics of actinic cheilitis (AC) and lip squamous cell carcinoma (LSCC) are well studied; however, they are based on studies limited to a single centre. Herein, we described the frequency of AC and LSCC submitted to microscopic examination from representative geographic regions of Brazil. A retrospective multicentre study was performed on biopsies obtained from 1953 to 2018 at 10 Brazilian oral and maxillofacial pathology centres. A total of 198,709 biopsy specimens were surveyed. Sociodemographic data and clinicopathologic characteristics were analysed. A total of 2017 cases of ACs (1.0%) and 850 cases of LSCCs (0.4%) were recorded. A strong fair-skinned (> 87%) male (> 70%) predilection was observed in both conditions. The mean age was 54.8 ± 18.7 for individuals with AC and 57.8 ± 19.0 for individuals with LSCC. The most commonly affected site was the lower lip (> 90%). This is a large multicentre study of AC and LSCC from Brazil. The frequency and clinicopathological features of AC and LSCC were similar to those described worldwide. This study provides robust and representative epidemiological data of these conditions for the scientific community.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669919 | PMC |
| http://dx.doi.org/10.1007/s12105-020-01142-2 | DOI Listing |
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