Objective: The aim of this study was to assess the accuracy and precision of the actual epidural depth (ND) and ultrasound (US) estimates of the distance from the skin to the epidural space in the transverse median plane (ED/TM) and paramedian sagittal oblique plane (ED/PSO) in patients who were not pregnant and who were undergoing unilateral inguinal hernia repair surgery under combined spinal epidural anaesthesia.
Methods: A total of 100 patients with the American Society of Anaesthesiology status I-III of either gender were recruited. All epidurals were inserted at the L3-4 intervertebral space, and the epidural needle was marked with a sterile marker. The ND was measured between the marker and the tip of the needle. The ED/TM and ED/PSO were assessed with a 2-5 MHz curved array probe at the L3-4 intervertebral space. The Pearson correlation coefficient and Lin's concordance correlation coefficient were used to assess the precision and the Bland-Altman test was used to assess the 95% limit of agreement.
Results: The ND was 48.98±6.91 mm, the ED/PSO was 48.92±6.91 mm and the ED/TM was 48.90±6.91 mm. The Pearson correlation coefficient between ND and ED/PSO was 0.995 (p<0.001) and 0.994 (p<0.001) with ED/TM. Lin's concordance correlation coefficient for ND and ED/PSO was 0.995 (95%CI [confidence interval]: 0.992-0.997), and 0.993 for ND and ED/TM (95% CI: 0.990-0.996). The 95% limit of agreement between ND and ED/PSO was 0.70-1.37, and for ND and ED/TM, it was 0.79-1.54.
Conclusion: Preprocedural ultrasound (US) scanning in both planes provides reliable estimates for actual epidural depth in non-pregnant patient population.
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http://dx.doi.org/10.5152/TJAR.2019.92342 | DOI Listing |
Brief Bioinform
November 2024
Department of Automation, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai 200240, China.
Studying the changes in cellular transcriptional profiles induced by small molecules can significantly advance our understanding of cellular state alterations and response mechanisms under chemical perturbations, which plays a crucial role in drug discovery and screening processes. Considering that experimental measurements need substantial time and cost, we developed a deep learning-based method called Molecule-induced Transcriptional Change Predictor (MiTCP) to predict changes in transcriptional profiles (CTPs) of 978 landmark genes induced by molecules. MiTCP utilizes graph neural network-based approaches to simultaneously model molecular structure representation and gene co-expression relationships, and integrates them for CTP prediction.
View Article and Find Full Text PDFBr J Surg
December 2024
Department of Anaesthesiology, Nara Medical University, Nara, Japan.
Background: The WHO Disability Assessment Schedule (WHODAS) 2.0 is widely used for detecting postoperative functional disability. Its responsiveness for detecting disability has been evaluated at 1 year after surgery, with no long-term evaluation.
View Article and Find Full Text PDFJpn J Ophthalmol
January 2025
Department of Ophthalmology, Kitasato Insititute Hospital, Kitasato University, Tokyo, Japan.
Purpose: Internal limiting membrane (ILM) is usually peeled simultaneously with epiretinal membrane (ERM), however, in eyes with glaucoma and ERM, ILM is preserved in order to prevent nerve fiber damage. The aim of this study was to evaluate if a new approach for ERM is effective to keep ILM during surgery.
Study Design: Retrospective consecutive case series.
J Funct Morphol Kinesiol
December 2024
Department of Sport Science, Universität Innsbruck, 6020 Innsbruck, Austria.
: Unlike road running, mountain and trail running typically cover longer distances and include uphill and downhill segments that impose unique physiological and mechanical demands on athletes. : This study aimed to identify morphological differences in the patellar and Achilles tendons between trail and road runners. Moreover, the potential influence of weekly mileage and accumulated positive elevation gain on the morphology of both tendons was obtained.
View Article and Find Full Text PDFGeriatrics (Basel)
January 2025
Graduate School of Health Sciences, Yamagata Prefectural University of Health Sciences, 260 Kamiyanagi, Yamagata 990-2212, Japan.
This study aimed to elucidate the relationship between early postoperative gait parameters after total hip arthroplasty (THA) and the Forgotten Joint Score-12 (FJS-12) score at the 2-year follow-up after surgery. In addition, the cutoff gait parameter values for predicting discomfort using specific FJS-12 subitems were evaluated. Among 313 patients who underwent THA between April and December 2019, 44 (14.
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