Surgical trauma induces a hormonal metabolic response which is partly responsible for postoperative catabolism. In this study 12 patients underwent cholecystectomy during isoflurane anaesthesia, six with a paravertebral block (PVB) in addition. Plasma concentrations of glucose, cortisol and adrenaline, and heart rate and arterial pressure were compared between the two groups. The patients with PVB showed a significantly diminished response to noxious stimuli.
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| http://dx.doi.org/10.1093/bja/61.6.652 | DOI Listing |
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