AI Article Synopsis

  • Autoimmune encephalitis is a brain condition that can be treated if caught early enough to avoid serious damage.
  • Identifying this condition is tough because it shows different symptoms, so patients might see different doctors.
  • Three cases were described: a woman had severe mood changes and seizures due to an antibody related to a tumor, one man had memory issues and got better, and another man had stiffness and other symptoms but responded well to treatment too.

Article Abstract

In recent years, there have been many developments in the field of autoimmune encephalitis. Autoimmune encephalitis is often treatable, and fast recognition and treatment are essential to prevent irreversible damage. Identification of patients with autoimmune encephalitis is challenging because patients display various symptoms and consequently present to different medical specialists. We describe 3 cases of autoimmune encephalitis due to different antibodies. A 23-year-old woman presented with acute psychosis, followed by seizures and autonomic dysfunction. She was diagnosed with anti-NMDAR encephalitis caused by antibodies that were triggered by ovarian teratoma. A 59-year-old man developed severe behavioural changes, memory deficits, and subtle faciobrachial dystonic seizures. He had anti-LGI1 encephalitis and recovered completely. The third patient was a 57-year-old man who presented with diarrhea and weight loss, and gradually developed progressive rigidity, myoclonus and ataxia over the course of several months. He was ultimately diagnosed with anti-DPPX encephalitis. All patients responded well to immunotherapy with (near-)complete recovery within months to years.

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