In 2016, the proportion of isolates with reduced susceptibility to azithromycin rose to 3.6%. A phylogenetic analysis of 334 isolates collected in 2016 revealed a single, geographically diverse lineage of isolates with MICs of 2 to 16 μg/ml that carried a mosaic-like locus, whereas the majority of isolates with MICs of ≥16 μg/ml appeared sporadically and carried 23S rRNA mutations. Continued molecular surveillance of isolates will identify new resistance mechanisms.
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| http://dx.doi.org/10.1128/AAC.02420-19 | DOI Listing |
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