The United States is facing a shortage of physicians for minorities and patients in disadvantaged areas. Many medical schools have pipeline programs to promote the interest of minority students in medicine. The Brody School of Medicine at East Carolina University established the Brody RISE program. Recruitment efforts targeted schools within Pitt County, NC. Students participate in interactive STEM activities and campus tours. Laupus Health Sciences Librarians developed interactive activities that engage critical thinking and teach anatomy and medical history. The organizers of the Brody RISE program continually evaluate and expand the program. Laupus Library continues to partner in these activities.
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http://dx.doi.org/10.1080/02763869.2019.1693225 | DOI Listing |
Curr Oncol
December 2024
Breast Center, São João University Hospital (ULS São João), 4200-319 Porto, Portugal.
(1) Background: Breast cancer (BC) has a high incidence in Europe, particularly in older adults. Traditionally under-represented in clinical trials, this age group is often undertreated due to ageism. This study aims to characterize frail older adults (≥70 years) with BC based on a comprehensive geriatric assessment, to guide individualized treatment decision-making.
View Article and Find Full Text PDFJGH Open
December 2024
Division of Hepatology, Sandra Atlas Bass Center for Liver Diseases and Transplantation Donald and Barbara Zucker School of Medicine, Northwell Health Manhasset New York USA.
Cureus
August 2024
Department of Physiology, Brody School of Medicine, East Carolina University, Greenville, USA.
Introduction Radiation therapy (RT) is the gold standard for many pelvic cancers and improves overall patient survival. However, pelvic RT is associated with increased sexual dysfunction and urinary incontinence. Although the side effects of pelvic RT are well-documented, the pathological mechanisms leading to pelvic organ dysfunction are unknown, and a preclinical model has not been established.
View Article and Find Full Text PDFAm J Physiol Endocrinol Metab
October 2024
Department of Kinesiology, East Carolina University, Greenville, North Carolina, United States.
Besides the well-recognized influence of maternal health on fetal in utero development, recent epidemiological studies appoint paternal preconception metabolic health as a significant factor in shaping fetal metabolic programming and subsequently offspring metabolic health; however, mechanisms behind these adaptations remain confined to animal models. To elucidate the effects of paternal obesity (P-OB) on infant metabolism in humans, we examined mesenchymal stem cells (MSCs), which give rise to infant tissue, remain involved in mature tissue maintenance, and resemble the phenotype of the offspring donor. Here, we assessed mitochondrial functional capacity, content, and insulin action in MSC from infants of fathers with overweight [body mass index (BMI: 25-30 kg/m); paternal overweight (P-OW)] or obesity (BMI ≥ 30 kg/m; P-OB) while controlling for maternal intrauterine environment.
View Article and Find Full Text PDFInfect Dis Ther
October 2024
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Introduction: Recurrent Clostridioides difficile infection (rCDI) often occurs after standard-of-care antibiotics. VOWST oral spores (VOS, previously SER-109), an FDA-approved orally administered microbiome therapeutic, is indicated to prevent rCDI following antibiotics for rCDI.
Objective, Design, And Patients: To evaluate safety and efficacy of VOS from two phase 3 trials, (randomized, placebo-controlled [ECOSPOR III: NCT03183128] and open-label, single arm [ECOSPOR IV: NCT03183141]) of 349 adults with rCDI and prevalent comorbidities.
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