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Individual differences in the distributional learning and overnight consolidation of the Mandarin level-falling tone contrast.
J Acoust Soc Am
December 2024
Division of Humanities, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.
In perceptual studies, musicality and pitch aptitude have been implicated in tone learning, while vocabulary size has been implicated in distributional (segment) learning. Moreover, working memory plays a role in the overnight consolidation of explicit-declarative L2 learning. This study examines how these factors uniquely account for individual differences in the distributional learning and consolidation of an L2 tone contrast, where learners are tonal language speakers, and the training is implicit.
View Article and Find Full Text PDFDeep profiling deconstructs features associated with memory CD8 T cell tissue residence.
Immunity
December 2024
Department of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address:
Tissue-resident memory CD8 T (Trm) cells control infections and cancer and are defined by their lack of recirculation. Because migration is difficult to assess, residence is usually inferred by putative residence-defining phenotypic and gene signature proxies. We assessed the validity and universality of residence proxies by integrating mouse parabiosis, multi-organ sampling, intravascular staining, acute and chronic infection models, dirty mice, and single-cell multi-omics.
View Article and Find Full Text PDFNeural evidence of implicit emotion regulation deficits: An explorative study of comparing PTSD with and without alcohol dependence.
J Affect Disord
December 2024
Key Laboratory of Adolescent Cyberpsychology and Behavior (Ministry of Education), Key Laboratory of Human Development and Mental Health of Hubei Province, School of Psychology, Central China Normal University, Wuhan, China. Electronic address:
Background: Previous studies have identified psychiatric comorbidity, including alcohol dependence (AD), as a significant factor in treating posttraumatic stress disorder (PTSD), there is a lack of evidence on how best to treat comorbid PTSD and AD. Poor emotion regulation may be a key potential mechanism of PTSD and AD comorbidity.
Methods: Seventy-four participants (48 women and 26 men) include three groups: a healthy control group (HC group, N = 20), a PTSD without alcohol dependence group (PTSD without AD group, N = 36), and a PTSD with alcohol dependence group (PTSD with AD group, N = 18).
Emotional intensity produces a linear relationship on conditioned learning but an inverted U-shaped effect on episodic memory.
Learn Mem
December 2024
Department of Psychiatry and Behavioral Sciences, University of Texas at Austin, Austin, Texas 78712, USA
Emotional intensity can produce both optimal and suboptimal effects on learning and memory. While emotional events tend to be better remembered, memory performance can follow an inverted U-shaped curve with increasing intensity. The strength of Pavlovian conditioning tends to increase linearly with the intensity of the aversive outcome, but leads to greater stimulus generalization.
View Article and Find Full Text PDFExplicit Memory, Implicit Memory, and the Hippocampus: Insights From Early Neuroimaging Studies.
Hippocampus
January 2025
Department of Psychology and Center for Brain Science, Harvard University, Cambridge, Massachusetts, USA.
During the 1980s and 1990s, much memory research focused on the differential role of the hippocampus in various forms of memory. My work on the distinction between explicit and implicit memory led me to become involved in several early neuroimaging studies that made use of cognitive paradigms to investigate the conditions in which hippocampal activity does and does not occur, and to address the theoretical implications of these findings. Here, I summarize two such projects and some of the personal backstory associated with them.
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