Promising antiviral, antimicrobial and therapeutic properties of green nanoceria.

Nanomedicine (Lond)

UNESCO UNISA Africa Chair in Nanosciences & Nanotechnology, College of Graduate Studies, University of South Africa, Muckleneuk Ridge, PO Box 392, Pretoria, Gauteng, South Africa.

Published: February 2020

To demonstrate synthesis of cerium oxide nanoparticles (CeO NPs) by a green method using , and investigate their therapeutic applications. Structural, vibrational and luminescent properties were established using x-ray diffraction, Fourier transformed infrared spectroscopy, Raman spectroscopy, ultraviolet absorption spectroscopy, selected area electron diffraction, electron microscopy and photolumincence spectroscopy. Therapeutic properties were established using different assays. CeO NPs were determined to be crystalline in nature with a grain size of approximately 14 nm. They had characteristic Ce-O vibration at 481 cm. Photoluminescence spectra revealed broad bands at 463 and 600 nm. ζ potential was recorded as -17.2 mV. Potent antimicrobial and antiviral properties with hemocompatibility were reported. Biosynthesized CeO NPs revealed multifunctional therapeutic properties.

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http://dx.doi.org/10.2217/nnm-2019-0368DOI Listing

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