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A Comprehensive Review on Polymer-Dispersed Liquid Crystals: Mechanisms, Materials, and Applications.
ACS Mater Au
January 2025
Liquid Crystal Research Laboratory, Department of Physics, University of Lucknow, Lucknow, Uttar Pradesh 226007, India.
Polymer-dispersed liquid crystals (PDLCs) stand at the intersection of polymer science and liquid crystal technology, offering a unique blend of optical versatility and mechanical durability. These composite materials are composed of droplets of liquid crystals interspersed in a matrix of polymeric materials, harnessing the optical properties of liquid crystals while benefiting from the structural integrity of polymers. The responsiveness of LCs combined with the mechanical rigidity of polymers make polymer/LC composites-where the polymer network or matrix is used to stabilize and modify the LC phase-extremely important for scientists developing novel adaptive optical devices.
View Article and Find Full Text PDFThe Changes in ICD-11 Related to Sexual Health and Dysfunction and Their Implication for Clinical Practice.
Turk Psikiyatri Derg
January 2025
The classification of sexual health-related conditions was reformulated in 11th revision of International Classification of Diseases (ICD-11) following current evidence, best practice, and taking human rights into consideration, which is expected to reflect and provide guidance for more integrative clinical approaches. Overcoming the artificial, yet historical, distinction between "organic" and "non-organic" conditions, sexual dysfunctions classified in the "Mental and Behavioral Disorders" and "Disorders of Genitourinary System" in ICD-10 were listed in a new chapter called "Conditions Related to Sexual Health." In practice, this approach has been consistently recommended.
View Article and Find Full Text PDFLower respiratory tract microbiome dysbiosis impairs clinical responses to immune checkpoint blockade in advanced non-small-cell lung cancer.
Clin Transl Med
January 2025
Department of Cell Biology, National Translational Science Center for Molecular Medicine, Fourth Military Medical University, Xi'an, China.
Background: Gut microbiome on predicting clinical responses to immune checkpoint inhibitors (ICIs) has been discussed in detail for decades, while microecological features of the lower respiratory tract within advanced non-small-cell lung cancer (NSCLC) are still relatively vague.
Methods: During this study, 26 bronchoalveolar lavage fluids (BALF) from advanced NSCLC participants who received immune checkpoint inhibitor monotherapy were performed 16S rRNA sequencing and untargeted metabolome sequencing to identify differentially abundant microbes and metabolic characteristics. Additionally, inflammatory cytokines and chemokines were also launched in paired BALF and serum samples by immunoassays to uncover their underlying correlations.
Global Use, Adaptation, and Sharing of Massive Open Online Courses for Emergency Health on the OpenWHO Platform: Survey Study.
J Med Internet Res
January 2025
Learning and Capacity Development Unit, Health Emergencies Programme, World Health Organization, Geneva, Switzerland.
Background: The COVID-19 pandemic demonstrated the global need for accessible content to rapidly train health care workers during health emergencies. The massive open access online course (MOOC) format is a broadly embraced strategy for widespread dissemination of trainings. Yet, barriers associated with technology access, language, and cultural context limit the use of MOOCs, particularly in lower-resource communities.
View Article and Find Full Text PDFBetween the lines: a discursive analysis of the non-specific low back pain literature.
Physiother Theory Pract
January 2025
RECOVER Injury Research Centre, The University of Queensland, Surgical Treatment and Rehabilitation Service (STARS), Herston, Australia.
Background: The term nonspecific low back pain (NSLBP) is often ambiguously defined and inconsistently used in scientific literature. Yet, there is limited discussion and reflection on the meaning of the term and how different meanings influence research and clinical practice.
Aim: The aim of this study was to critically analyze the meaning of NSLBP in scientific literature and its consequent influence on research and clinical practice.
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