Primary cutaneous aspergillosis (PCA) occurs through inoculation of fungal spores directly into the skin from the environment through disrupted skin such as in burns, surgery or penetrating trauma patients. Most cases reported in literature were in the immunocompromised, rarely in immunocompetent patients. The characteristic lesion of cutaneous aspergillosis is a black eschar on a red plaque, or nodule at the site of skin injury. The diagnosis of PCA can be made by identifying hyphal forms on routine H&E staining or special stains such as periodic acid-Schiff or Gomori methenamine-silver stains on skin biopsy and by fungal cultures. We report a case of an 80-year-old farmer who developed cutaneous aspergillosis after a surgical procedure without any systemic spread. The diagnosis was made by histopathology and tissue fungal cultures. He was treated with incision and drainage followed by oral voriconazole for 4 weeks; which led to clinical recovery.
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http://dx.doi.org/10.1136/bcr-2019-233020 | DOI Listing |
J Infect Chemother
November 2024
Infectious Diseases Department, Ramón y Cajal University Hospital, Madrid, Spain; University of Alcalá, IRYCIS, CIBERINFEC, Spain.
J Clin Microbiol
December 2024
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Rev Med Interne
November 2024
Service de médecine interne, CHU de Saint-Étienne, hôpital Nord, Saint-Étienne, France. Electronic address:
J Med Case Rep
September 2024
Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, minami1-nishi16Chuo-Ku, Sapporo, Hokkaido, 060-8543, Japan.
Granulomatosis with polyangiitis (GPA) is a rare multisystem disease characterized by vasculitis affecting small vessels, resulting in the formation of necrotising granulomata, primarily affecting the lungs, the upper respiratory tract, and kidneys. Almost all patients have upper and lower respiratory involvement; up to 85% of patients with GPA develop kidney disease within two years of diagnosis. Cutaneous, neurological, and ocular manifestations are also seen with varying frequencies.
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